HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 718
+	Hs
		990892 ZO1_HUMAN (1-1748): 0: 925: 100.00		DLG5_HUMAN (171-610): 2.12e-15: 82.7: 17.71
+	Hs
		990961 ZO1_HUMAN (1-1748): 0: 925: 100.00		MRCKB_HUMAN (401-706): 2.71e-13: 75.8: 13.67
+	Hs
		990832 ZO1_HUMAN (1-1748): 0: 925: 100.00		CGNL1_HUMAN (31-319): 2.3e-09: 63.1: 10.00
+	Hs
		943690 DLG3_HUMAN (21-427): 4.69e-51: 197: 17.51		KRT85_HUMAN (254-644): 3.08e-30: 127: 14.29
+	Hs
		1202433 DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Hs
		1202477 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Mm
		936586 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		ROCK2_MOUSE (102-661): 8.5e-13: 74.2: 15.96
+	Hs
		280085 MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61		DAPLE_HUMAN (58-493): 1.77e-11: 70.2: 12.07
+	Hs
		1255142 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		DLG5_HUMAN (171-610): 2.12e-15: 82.7: 17.71
+	Hs
		1354499 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98
+	Hs
		1268108 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03