HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 684
+	Dm
		980077 Q9VHK4_DROME (14-1358): 1.93e-170: 556: 26.59		KELC_DROME (437-682): 8.05e-51: 193: 15.85
+	Hs
		1262087 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00
+	Hs
		159127 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KLHL2_HUMAN (350-483): 4.59e-24: 109: 22.79
+	Rn
		677801 DLG4_RAT (1-112): 1.95e-27: 122: 29.92		KLH17_RAT (311-483): 7.11e-22: 102: 14.53