Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: KIRR1 (Q96J84)
Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1)
Gene: KIRREL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 12865409, 12578837, 22262837
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, molecular sieving, x ray scattering
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0050839 - cell adhesion molecule binding
GO:0098609 - cell-cell adhesion
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1748
Hs

1 757
+ Dm
+ Dm
+ Mm
+ Rn
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024