HitPredict

Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RELB (Q04863)
Transcription factor RelB
Gene: RELB

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	11748221
Identification Methods	pull down, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0017053 - transcription repressor complex GO:0045063 - T-helper 1 cell differentiation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 215 Mm			1 558
+	Hs
		481247 HMGB1_HUMAN (1-174): 1.02e-41: 142: 100.00		TF65_HUMAN (90-506): 1.45e-150: 445: 42.11
+	Hs
		659215 SP100_HUMAN (25-178): 4.43e-32: 124: 87.66		TF65_HUMAN (90-506): 1.45e-150: 445: 42.11
+	Hs
		1024013 TFAM_HUMAN (9-189): 1.33e-32: 119: 20.79		TF65_HUMAN (90-506): 1.45e-150: 445: 42.11
+	Hs
		481086 HMGB1_HUMAN (1-174): 1.02e-41: 142: 100.00		NFKB1_HUMAN (67-397): 9.88e-127: 396: 36.73
+	Hs
		626080 HMGB2_HUMAN (1-187): 5.71e-40: 137: 82.89		NFKB1_HUMAN (67-397): 9.88e-127: 396: 36.73
+	Hs
		626177 TFAM_HUMAN (9-189): 1.33e-32: 119: 20.79		NFKB1_HUMAN (67-397): 9.88e-127: 396: 36.73
+	Dm
		121517 M9PFG6_DROME (7-95): 4.89e-24: 100: 21.35		NFKB1_DROME (80-422): 4.52e-108: 347: 30.03
+	Hs
		1024026 TFAM_HUMAN (9-189): 1.33e-32: 119: 20.79		NFAC2_HUMAN (55-532): 1.73e-100: 326: 19.33
+	Hs
		1106372 CIC_HUMAN (57-210): 2.52e-30: 119: 19.48		NFAC2_HUMAN (55-532): 1.73e-100: 326: 19.33
+	Hs
		1091755 CIC_HUMAN (57-210): 2.52e-30: 119: 19.48		NFAC3_HUMAN (64-557): 3.24e-99: 325: 17.64
+	Hs
		1065177 SSRP1_HUMAN (53-164): 9.75e-28: 111: 37.50		NFAC2_HUMAN (55-532): 1.73e-100: 326: 19.33
+	Hs
		340930 CIC_HUMAN (57-210): 2.52e-30: 119: 19.48		NFAC1_HUMAN (43-513): 6.77e-95: 311: 18.64
+	Dm
		583365 HMG2_DROME (83-191): 1.28e-09: 59: 19.64		DORS_DROME (77-413): 2.01e-107: 346: 39.12
+	Hs
		1024040 TFAM_HUMAN (9-189): 1.33e-32: 119: 20.79		NFAC4_HUMAN (17-526): 5.46e-78: 265: 17.59
+	Hs
		1133407 CIC_HUMAN (57-210): 2.52e-30: 119: 19.48		NFAC4_HUMAN (17-526): 5.46e-78: 265: 17.59
+	Hs
		321986 CIC_HUMAN (57-210): 2.52e-30: 119: 19.48		NFAT5_HUMAN (89-526): 3.14e-74: 259: 18.51