Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1
Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16267105 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001530 - lipopolysaccharide binding GO:0002218 - activation of innate immune response GO:0005769 - early endosome GO:0006954 - inflammatory response GO:0032689 - negative regulation of type II interferon production and 15 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
