Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1
Interactor 2: TLR2 (Q9QUN7)
Toll-like receptor 2 (CD antigen CD282)
Gene: TLR2
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16267105 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0006954 - inflammatory response GO:0032728 - positive regulation of interferon-beta production GO:0032731 - positive regulation of interleukin-1 beta production GO:0032735 - positive regulation of interleukin-12 production GO:0032755 - positive regulation of interleukin-6 production and 4 others more... |
| Homologous interactions | 6 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025