HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: RRP1B (Q14684)
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)
Gene: RRP1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	19710015, 20926688, 23604122
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0043484 - regulation of RNA splicing
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 758
+	Hs
		1028912 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Hs
		516520 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Hs
		1057482 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Hs
		1031330 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Hs
		965152 PABP3_HUMAN (8-203): 1.09e-33: 129: 16.18		ANK2_HUMAN (222-733): 8.46e-28: 123: 13.03
+	Hs
		516595 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		KMT2C_HUMAN (211-746): 8e-10: 64.9: 9.09
+	Hs
		516609 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		TITIN_HUMAN (224-747): 2.27e-09: 63.3: 9.36
+	Hs
		1031405 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		TITIN_HUMAN (224-747): 2.27e-09: 63.3: 9.36