HitPredict

Interactor 1: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 4544 Hs			1 451
+	Hs
		992702 LRP1_HUMAN (24-4544): 0: 3520: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		933414 LRP1_HUMAN (24-4544): 0: 3520: 100.00		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		933769 LRP1_HUMAN (24-4544): 0: 3520: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Dm
		415586 NOTCH_DROME (2434-2789): 1.13e-10: 70.6: 11.72		TBA1_DROME (1-439): 0: 711: 97.95