HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: SCAFB (Q99590)
Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129)
Gene: SCAF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	9447963, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1463
+	Hs
		1028784 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		SCAFB_HUMAN (1-1463): 0: 657: 100.00
+	Hs
		1029053 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		SCAFB_HUMAN (1-1463): 0: 657: 100.00
+	Hs
		952095 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		SCAFB_HUMAN (1-1463): 0: 657: 100.00
+	Hs
		1029143 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		PHRF1_HUMAN (37-1419): 2.87e-54: 211: 10.71
+	Hs
		1028822 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		1029097 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		993833 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		992936 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		1028547 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		MDC1_HUMAN (212-1082): 2.36e-25: 117: 9.88
+	Hs
		1028977 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		RBBP6_HUMAN (306-1122): 4.56e-26: 119: 11.74
+	Hs
		993755 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		RBBP6_HUMAN (306-1122): 4.56e-26: 119: 11.74
+	Hs
		992772 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		MDC1_HUMAN (212-1082): 2.36e-25: 117: 9.88
+	Hs
		1028876 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		1029050 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		MINT_HUMAN (292-1220): 3.07e-10: 67.6: 8.93
+	Hs
		1029163 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		993872 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		992995 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		952014 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		RBBP6_HUMAN (306-1122): 4.56e-26: 119: 11.74
+	Hs
		516749 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		516609 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		TITIN_HUMAN (986-1460): 9.74e-10: 65.8: 9.62