HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: SAV (Q9VCR6)
Scaffold protein salvador (Shar-pei)
Gene: SAV

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	24114784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 211 Dm			1 608
+	Hs
		125348 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		WWP2_HUMAN (253-566): 9.33e-64: 227: 15.53
+	Hs
		337392 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		NEDD4_HUMAN (71-601): 3.77e-90: 305: 15.59
+	Hs
		789045 ABL2_HUMAN (4-138): 3.23e-23: 98.6: 35.71		NEDD4_HUMAN (71-601): 3.77e-90: 305: 15.59
+	Hs
		412081 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		NEDD4_HUMAN (71-601): 3.77e-90: 305: 15.59
+	Hs
		433282 YES_HUMAN (160-211): 1.47e-10: 61.9: 25.93		NEDD4_HUMAN (71-601): 3.77e-90: 305: 15.59
+	Hs
		522850 SRC_HUMAN (160-211): 1.73e-10: 61.5: 25.93		NEDD4_HUMAN (71-601): 3.77e-90: 305: 15.59
+	Dm
		993204 GRAP_DROME (1-211): 8.97e-63: 195: 100.00		Q9VFD3_DROME (310-510): 4.48e-32: 135: 19.56
+	Hs
		125051 GRAP2_HUMAN (3-56): 7.35e-11: 62.2: 35.19		WWP2_HUMAN (253-566): 9.33e-64: 227: 15.53
+	Hs
		454848 FGR_HUMAN (160-211): 3.92e-11: 63.5: 25.93		SMUF1_HUMAN (387-593): 1.21e-44: 171: 12.85
+	Hs
		337535 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		NED4L_HUMAN (50-326): 6.31e-31: 131: 12.15
+	Hs
		789085 ABL2_HUMAN (4-138): 3.23e-23: 98.6: 35.71		NED4L_HUMAN (50-326): 6.31e-31: 131: 12.15
+	Hs
		337393 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		YAP1_HUMAN (332-521): 2.15e-28: 121: 18.18
+	Hs
		557636 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		YAP1_HUMAN (332-521): 2.15e-28: 121: 18.18
+	Hs
		802529 CRK_HUMAN (48-209): 9e-20: 87: 29.69		YAP1_HUMAN (332-521): 2.15e-28: 121: 18.18
+	Hs
		433283 YES_HUMAN (160-211): 1.47e-10: 61.9: 25.93		YAP1_HUMAN (332-521): 2.15e-28: 121: 18.18
+	Hs
		433639 LYN_HUMAN (97-211): 1.71e-10: 61.5: 17.09		YAP1_HUMAN (332-521): 2.15e-28: 121: 18.18
+	Hs
		412307 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		ITCH_HUMAN (75-327): 1.8e-18: 91.8: 13.95
+	Hs
		1078893 ITSN1_HUMAN (44-209): 1.56e-11: 65: 11.48		ITCH_HUMAN (75-327): 1.8e-18: 91.8: 13.95
+	Hs
		275221 GRAP2_HUMAN (3-56): 7.35e-11: 62.2: 35.19		ITCH_HUMAN (75-327): 1.8e-18: 91.8: 13.95