HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~FH2, Actin~WH2
Common GO terms	GO:0005884 - actin filament
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1249
+	Hs
		952859 ACTB_HUMAN (1-375): 0: 604: 98.93		INF2_HUMAN (1-1249): 0: 874: 100.00
+	Hs
		995624 ACTC_HUMAN (2-375): 0: 594: 94.39		INF2_HUMAN (1-1249): 0: 874: 100.00
+	Hs
		953134 ACTB_HUMAN (1-375): 0: 604: 98.93		DIAP3_HUMAN (10-1092): 0: 664: 21.40
+	Hs
		252430 ACTB_HUMAN (1-375): 0: 604: 98.93		DIAP1_HUMAN (10-1038): 0: 618: 21.64
+	Hs
		252442 ACTC_HUMAN (2-375): 0: 594: 94.39		DIAP1_HUMAN (10-1038): 0: 618: 21.64
+	Hs
		953207 ACTB_HUMAN (1-375): 0: 604: 98.93		DAAM1_HUMAN (4-1016): 1.04e-179: 560: 21.43
+	Hs
		993299 ACTG_HUMAN (1-375): 0: 604: 100.00		FMNL2_HUMAN (10-1000): 3.07e-166: 525: 19.11
+	Hs
		953218 ACTB_HUMAN (1-375): 0: 604: 98.93		FHOD1_HUMAN (15-1069): 1.71e-158: 507: 14.18
+	Hs
		993405 ACTG_HUMAN (1-375): 0: 604: 100.00		FHOD1_HUMAN (15-1069): 1.71e-158: 507: 14.18
+	Sc
		824659 ACT_YEAST (1-375): 0: 592: 89.07		BNR1_YEAST (156-1000): 1.96e-100: 351: 16.23
+	Hs
		1200992 ACTBL_HUMAN (2-375): 0: 734: 91.44		FMNL3_HUMAN (43-405): 3.52e-53: 205: 19.05
+	Hs
		977747 ACTA_HUMAN (2-375): 0: 594: 94.39		FMNL3_HUMAN (43-405): 3.52e-53: 205: 19.05
+	Sp
		534536 ACT_SCHPO (1-375): 0: 594: 91.47		CDC12_SCHPO (1-281): 6.75e-21: 101: 15.72
+	Hs
		953147 ACTB_HUMAN (1-375): 0: 604: 98.93		FMN2_HUMAN (495-827): 8.37e-11: 68.9: 25.71
+	Hs
		993358 ACTG_HUMAN (1-375): 0: 604: 100.00		FMN2_HUMAN (495-827): 8.37e-11: 68.9: 25.71
+	Hs
		995856 ACTC_HUMAN (2-375): 0: 594: 94.39		FMN2_HUMAN (495-827): 8.37e-11: 68.9: 25.71