HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21113135
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 298
+	Hs
		906737 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		BIRC7_HUMAN (1-298): 4.55e-104: 307: 100.00
+	Hs
		906793 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		BIRC6_HUMAN (54-252): 7.19e-36: 138: 21.10
+	Hs
		1361437 UB2D4_HUMAN (4-157): 3.69e-75: 222: 34.42		MYLIP_HUMAN (152-297): 4e-26: 108: 22.45
+	Hs
		906722 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		MYLIP_HUMAN (152-297): 4e-26: 108: 22.45
+	Hs
		982263 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		MYLIP_HUMAN (152-297): 4e-26: 108: 22.45
+	Hs
		906733 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		MIB2_HUMAN (236-297): 7.75e-23: 100: 38.71
+	Hs
		302218 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		NEUL1_HUMAN (167-298): 1.18e-22: 99.6: 22.46
+	Hs
		982273 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		MIB2_HUMAN (236-297): 7.75e-23: 100: 38.71
+	Hs
		1295603 UB2D4_HUMAN (4-157): 3.69e-75: 222: 34.42		MIB1_HUMAN (206-296): 7.32e-20: 91.6: 25.28
+	Hs
		906657 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		BIRC3_HUMAN (238-298): 4.64e-20: 92: 70.97
+	Hs
		906699 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		MIB1_HUMAN (206-296): 7.32e-20: 91.6: 25.28
+	Hs
		982180 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		BIRC3_HUMAN (238-298): 4.64e-20: 92: 70.97
+	Hs
		982235 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		MIB1_HUMAN (206-296): 7.32e-20: 91.6: 25.28
+	Hs
		906658 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		BIRC2_HUMAN (84-281): 5.34e-19: 88.9: 23.23
+	Hs
		982181 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		BIRC2_HUMAN (84-281): 5.34e-19: 88.9: 23.23
+	Hs
		1399328 UB2D4_HUMAN (4-157): 3.69e-75: 222: 34.42		BIRC8_HUMAN (1-91): 5.56e-17: 80: 17.20
+	Hs
		906750 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		BIRC8_HUMAN (1-91): 5.56e-17: 80: 17.20
+	Hs
		1022814 UB2D4_HUMAN (4-157): 3.69e-75: 222: 34.42		XIAP_HUMAN (1-96): 3.49e-13: 71.6: 19.19
+	Hs
		906644 UB2D1_HUMAN (4-157): 7.95e-75: 221: 33.12		XIAP_HUMAN (1-96): 3.49e-13: 71.6: 19.19
+	Hs
		982166 UB2D2_HUMAN (4-157): 2.77e-74: 220: 35.07		XIAP_HUMAN (1-96): 3.49e-13: 71.6: 19.19