HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: RBBP6 (Q7Z6E9)
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)
Gene: RBBP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0006260 - DNA replication
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 1792
+	Hs
		996715 SSRP1_HUMAN (1-709): 0: 805: 100.00		NIPBL_HUMAN (880-1382): 5.38e-11: 70.3: 18.50
+	Hs
		230347 SSRP1_HUMAN (1-709): 0: 805: 100.00		ZC3H1_HUMAN (679-1650): 2.57e-10: 68: 12.68
+	Hs
		818382 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98
+	Hs
		818819 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78
+	Hs
		818268 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		BD1L1_HUMAN (851-1782): 4.77e-20: 100: 13.46
+	Hs
		1243843 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78
+	Hs
		727947 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		PRC2C_HUMAN (87-1452): 1.6e-12: 75.4: 8.27
+	Hs
		818266 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78
+	Hs
		727830 SOX5_HUMAN (441-648): 2.62e-30: 129: 19.23		PRC2C_HUMAN (87-1452): 1.6e-12: 75.4: 8.27
+	Hs
		818155 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		NIPBL_HUMAN (880-1382): 5.38e-11: 70.3: 18.50
+	Hs
		617319 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		NIPBL_HUMAN (880-1382): 5.38e-11: 70.3: 18.50
+	Hs
		449779 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07