HitPredict

Interactor 1: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	23665581, 32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 790 Hs			1 306
+	Hs
		853870 NCBP1_HUMAN (1-790): 0: 1180: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		516479 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		998037 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Dm
		1180175 NCBP1_DROME (1-790): 0: 1081: 57.27		NCBP2_DROME (147-292): 9.4e-34: 122: 20.41
+	Sp
		145203 NCBP1_SCHPO (3-664): 0: 652: 21.31		PAB2_SCHPO (107-255): 3.12e-34: 124: 48.32
+	Sc
		376713 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		PABP_YEAST (143-260): 3.27e-19: 89.6: 20.17
+	Sc
		710167 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		HRB1_YEAST (153-268): 1.5e-16: 81.4: 29.51
+	Sc
		693981 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		PUB1_YEAST (165-255): 5.29e-09: 58.8: 18.48