HitPredict

Interactor 1: DMWD (Q09019)
Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9)
Gene: DMWD

Interactor 2: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0043204 - perikaryon
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 3526
+	Hs
		929596 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		792949 LIS1_HUMAN (61-356): 1.01e-54: 194: 12.09		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		903109 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		196984 PRP4_HUMAN (62-311): 1.14e-28: 122: 14.40		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		903418 FBXW7_HUMAN (75-349): 3.2e-27: 119: 7.77		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		903349 WDR5B_HUMAN (360-666): 3.59e-27: 114: 12.46		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		903077 WDR5_HUMAN (402-646): 6.73e-18: 87.6: 7.97		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Sp
		140390 TAF73_SCHPO (214-446): 5.65e-57: 206: 18.70		TAF5_SCHPO (3161-3476): 1.69e-17: 91.9: 10.94
+	Hs
		1302754 TBL1R_HUMAN (321-629): 1.93e-32: 133: 12.84		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		209416 WDR5_HUMAN (402-646): 6.73e-18: 87.6: 7.97		PLRG1_HUMAN (2934-3299): 1.42e-38: 155: 13.66
+	Hs
		1263249 FBXW7_HUMAN (75-349): 3.2e-27: 119: 7.77		RUFY2_HUMAN (3427-3523): 2.22e-27: 123: 31.96
+	Hs
		245630 TBL1Y_HUMAN (321-637): 4.59e-33: 135: 12.76		TBL1X_HUMAN (2950-3109): 6.05e-14: 80: 14.72
+	Hs
		245546 TBL1X_HUMAN (321-629): 1.44e-32: 134: 13.07		TBL1X_HUMAN (2950-3109): 6.05e-14: 80: 14.72
+	Hs
		1309163 TBL1Y_HUMAN (321-637): 4.59e-33: 135: 12.76		TBL1R_HUMAN (2950-3109): 1.63e-13: 78.4: 12.88
+	Hs
		245633 TBL1X_HUMAN (321-629): 1.44e-32: 134: 13.07		TBL1R_HUMAN (2950-3109): 1.63e-13: 78.4: 12.88
+	Hs
		1074780 TAF5_HUMAN (69-312): 5.57e-22: 103: 13.93		TAF5_HUMAN (2800-3126): 8.34e-22: 106: 12.54