HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: DPF3 (Q92784)
Zinc finger protein DPF3 (BRG1-associated factor 45C) (BAF45C) (Zinc finger protein cer-d4)
Gene: DPF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35945219
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0007399 - nervous system development GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 378
+	Hs
		998619 EP300_HUMAN (1-2414): 0: 1113: 100.00		CHD3_HUMAN (61-371): 5.99e-51: 185: 15.76
+	Hs
		998717 EP300_HUMAN (1-2414): 0: 1113: 100.00		CHD4_HUMAN (62-371): 1.89e-42: 160: 15.21
+	Hs
		998941 EP300_HUMAN (1-2414): 0: 1113: 100.00		KAT6A_HUMAN (226-378): 1.35e-34: 137: 40.91
+	Mm
		70929 EP300_MOUSE (1-2414): 0: 1090: 93.01		CHD4_MOUSE (62-371): 3.04e-42: 159: 15.21
+	Dm
		115971 M9PH39_DROME (430-2323): 0: 769: 36.52		CHDM_DROME (64-365): 2.1e-46: 172: 18.79
+	Dm
		116024 M9PH39_DROME (430-2323): 0: 769: 36.52		Q9W1H0_DROME (257-375): 2.63e-19: 92.1: 25.00
+	Hs
		1067079 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		REQU_HUMAN (1-377): 1.96e-89: 276: 61.08
+	Hs
		1018704 BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31		CHD3_HUMAN (61-371): 5.99e-51: 185: 15.76
+	Hs
		331912 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		NSD2_HUMAN (92-368): 1.52e-34: 137: 16.23
+	Hs
		1059944 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		CHD4_HUMAN (62-371): 1.89e-42: 160: 15.21
+	Hs
		631414 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		CHD3_HUMAN (61-371): 5.99e-51: 185: 15.76
+	Hs
		631426 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		CHD4_HUMAN (62-371): 1.89e-42: 160: 15.21
+	Hs
		1059625 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		CHD4_HUMAN (62-371): 1.89e-42: 160: 15.21
+	Hs
		782401 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		KDM5C_HUMAN (295-375): 4.97e-24: 106: 37.81
+	Hs
		1067099 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		NSD1_HUMAN (62-369): 2e-40: 154: 13.35
+	Hs
		631520 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		PHF10_HUMAN (194-365): 4.58e-37: 142: 31.98
+	Hs
		975255 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		KMT2A_HUMAN (81-376): 4.05e-35: 139: 14.33
+	Hs
		331723 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		NSD2_HUMAN (92-368): 1.52e-34: 137: 16.23
+	Hs
		331815 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		NSD2_HUMAN (92-368): 1.52e-34: 137: 16.23
+	Hs
		666549 BRD8_HUMAN (965-1183): 9.91e-16: 86: 19.18		KDM5A_HUMAN (298-375): 1.57e-25: 110: 36.71