Protein: SHLD1
Shieldin complex subunit 1 (RINN1-REV7-interacting novel NHEJ regulator 3) (Shield complex subunit 1)

Gene: SHLD1
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q8IYI0

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0002208 - somatic diversification of immunoglobulins involved in immune response
GO:0005694 - chromosome
GO:0006281 - DNA repair
GO:0035861 - site of double-strand break

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1289794

SHLD2
Shieldin complex subunit 2

3

1

Small-scale

0.674

High

1315090

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

3

1

Small-scale

0.674

High

1315086

SHLD1
Shieldin complex subunit 1

1

0

Small-scale

0.458

High

1253263

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.426

High

868207

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.316

High

1179178

CTC1
CST complex subunit CTC1

2

0

Small-scale

0.305

High

1113643

CUL3
Cullin-3

1

0

High-throughput

0.279

Low

47370

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

109456

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

246031

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301545

WFS1
Wolframin

1

0

High-throughput

0.268

Low

415704

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

843748

HD
Huntingtin

1

0

High-throughput

0.268

Low

1279623

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1315087

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

1315088

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.265

Low

569120

T2FB
General transcription factor IIF subunit 2

1

0

Small-scale

0.249

Low

1315089

STN1
CST complex subunit STN1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025