Protein: SHLD3
Shieldin complex subunit 3 (REV7-interacting novel NHEJ regulator 1) (Shield complex subunit 3)

Gene: SHLD3
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q6ZNX1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0002208 - somatic diversification of immunoglobulins involved in immune response
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1253270

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.561

High

681422

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.445

High

998463

H31
Histone H3.1

1

1

High-throughput

0.445

High

1016969

H33
Histone H3.3

1

1

High-throughput

0.445

High

482155

RET1
Retinol-binding protein 1

1

0

High-throughput

0.426

High

485663

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.426

High

528279

THIO
Thioredoxin

1

0

High-throughput

0.426

High

681669

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.426

High

700913

PSB4
Proteasome subunit beta type-4

1

0

High-throughput

0.426

High

925939

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.426

High

941191

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.426

High

960461

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.426

High

973747

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.426

High

973957

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.426

High

1147187

ELOB
Elongin-B

1

0

High-throughput

0.426

High

1154855

NEDD8
Ubiquitin-like protein NEDD8

1

0

High-throughput

0.426

High

1253261

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.426

High

1253263

SHLD1
Shieldin complex subunit 1

1

0

High-throughput

0.426

High

91638

C9JAW5
HIG1 domain-containing protein

1

0

High-throughput

0.232

Low

182148

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low

347122

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.232

Low

354352

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.232

Low

462785

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.232

Low

528466

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.232

Low

665448

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.232

Low

679358

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.232

Low

716438

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.232

Low

986855

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

0

High-throughput

0.232

Low

1117102

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

1253259

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.232

Low

1253260

PAGE2
P antigen family member 2

1

0

High-throughput

0.232

Low

1253262

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.232

Low

1253264

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

0

High-throughput

0.232

Low

1253265

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.232

Low

1253266

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.232

Low

1253267

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.232

Low

1253268

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.232

Low

1253269

TOM7
Mitochondrial import receptor subunit TOM7 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025