Protein: CACT
NF-kappa-B inhibitor cactus

Gene: CACT
Organism: Drosophila melanogaster
Interactions: 48
UniProt ID: Q03017

Gene Ontology (top 5):
GO:0002789 - negative regulation of antifungal peptide production
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009950 - dorsal/ventral axis specification
GO:0009953 - dorsal/ventral pattern formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

583362

DORS
Embryonic polarity protein dorsal

17

20

Small-scale

0.987

High

1022286

DIF
Dorsal-related immunity factor Dif

5

19

Small-scale

0.924

High

1040530

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

2

20

Small-scale

0.825

High

1040521

NFKB1
Nuclear factor NF-kappa-B p110 subunit

2

20

Small-scale

0.807

High

1040512

CACT
NF-kappa-B inhibitor cactus

2

20

Small-scale

0.775

High

467107

CSK2A
Casein kinase II subunit alpha

2

3

Small-scale

0.727

High

746381

GPRK2
G protein-coupled receptor kinase 2

1

11

Small-scale

0.618

High

305462

O77430
GEO01111p1

1

6

High-throughput

0.590

High

1040518

Q7KNM2
Dorsal interacting protein 4

1

14

Small-scale

0.561

High

1040525

Q9V393
Kurtz arrestin

1

3

Small-scale

0.561

High

1040538

CATIN
Splicing factor Cactin

1

5

Small-scale

0.529

High

1040517

MERH
Moesin/ezrin/radixin homolog 2

1

20

High-throughput

0.508

High

1040524

FMR1
Fragile X messenger ribonucleoprotein 1 homolog

1

7

High-throughput

0.508

High

1040526

Q9V3E9
RNA polymerase II-associated protein 3

1

20

High-throughput

0.508

High

1040545

Q9XYW6
E3 ubiquitin-protein ligase CHIP

1

17

High-throughput

0.508

High

1040514

KPEL
Serine/threonine-protein kinase pelle

1

5

Small-scale

0.501

High

1040523

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

10

High-throughput

0.494

High

653070

TUBE
Protein Tube

1

0

Small-scale

0.493

High

1040532

Q9VH77
mannose-6-phosphate isomerase

1

0

High-throughput

0.486

High

1040515

CANA
Calpain-A

1

2

Small-scale

0.479

High

1040516

DIAP2
Death-associated inhibitor of apoptosis 2

1

11

High-throughput

0.479

High

1040527

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

6

High-throughput

0.479

High

58338

A1ZBL2
FI17509p1

1

2

High-throughput

0.464

High

930422

CNN
Centrosomin

1

8

High-throughput

0.464

High

1040529

Q9VEY1
Uncharacterized protein, isoform A

1

3

High-throughput

0.464

High

1040536

Q9VPZ5
GH04232p

1

1

High-throughput

0.464

High

1040537

Q9VQK1
Ccdc85

1

2

High-throughput

0.464

High

1040539

Q9VRV5
D19A

1

1

High-throughput

0.464

High

1040540

Q9VTP5
RE41410p

1

1

High-throughput

0.464

High

95394

E1JJ90
Meiosis-specific nuclear structural protein 1

1

3

High-throughput

0.439

High

1040522

Q95TZ7
GH19182p

1

6

High-throughput

0.439

High

1040541

Q9VTR8
Uncharacterized protein, isoform B

1

15

High-throughput

0.439

High

1040543

Q9W289
Golgi matrix protein 130 kD

1

10

High-throughput

0.439

High

1040534

Q9VM62
LD34181p

1

1

High-throughput

0.437

High

263442

O61348
Bobby sox

1

10

High-throughput

0.417

High

1040519

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

1

High-throughput

0.417

High

1040533

Q9VHR7
Meiosis-specific nuclear structural protein 1

1

4

High-throughput

0.417

High

1040520

Q8MRC3
Splicing factor Cactin

1

2

High-throughput

0.348

High

51657

NUP75
Nuclear pore complex protein Nup75

1

0

High-throughput

0.265

Low

51975

A1Z6J6
Uncharacterized protein

1

0

High-throughput

0.265

Low

55587

A1Z9I0
Cathepsin propeptide inhibitor domain-containing protein

1

0

High-throughput

0.265

Low

1040513

PROD
Proline dehydrogenase 1, mitochondrial

1

0

High-throughput

0.265

Low

1040528

CP6T3
Probable cytochrome P450 6t3

1

0

High-throughput

0.265

Low

1040531

Q9VFP5
Kotsubu

1

0

High-throughput

0.265

Low

1040535

Q9VNK8
FI16513p1

1

0

High-throughput

0.265

Low

1040542

Q9VWG6
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1040544

Q9W4E0
GH14578p

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025