Protein: UMPS
Uridine 5'-monophosphate synthase (UMP synthase) (Rudimentary-like protein) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)]

Gene: UMPS, r-l
Organism: Drosophila melanogaster
Interactions: 38
UniProt ID: Q01637

Gene Ontology (top 5):
GO:0004588 - orotate phosphoribosyltransferase activity
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 - UMP biosynthetic process
GO:0019856 - pyrimidine nucleobase biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654238

DDX6
ATP-dependent RNA helicase me31b

1

2

High-throughput

0.437

High

1031644

Q8IMG1
Uncharacterized protein, isoform C

1

1

High-throughput

0.437

High

1031645

AKT1
RAC serine/threonine-protein kinase

1

1

High-throughput

0.437

High

1031655

Q9VEV3
Tetratricopeptide repeat protein 1

1

4

High-throughput

0.437

High

1031656

Q9VHI8
Uncharacterized protein, isoform A

1

1

High-throughput

0.437

High

1031666

Q9W2K8
High mobility group protein 2

1

1

High-throughput

0.437

High

583361

DORS
Embryonic polarity protein dorsal

1

2

High-throughput

0.407

High

1022285

DIF
Dorsal-related immunity factor Dif

1

2

High-throughput

0.407

High

1031639

Q24044
Cell division cycle protein 20 homolog

1

1

High-throughput

0.407

High

1031650

Q9V9U3
LD45254p

1

1

High-throughput

0.407

High

1031664

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.407

High

1031668

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.407

High

197511

SPS1
Inactive selenide, water dikinase-like protein

2

0

High-throughput

0.298

High

575841

CCNA
G2/mitotic-specific cyclin-A

2

0

High-throughput

0.298

High

613950

SGG
Protein kinase shaggy

2

0

High-throughput

0.298

High

1031646

Q960K8
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

2

0

High-throughput

0.298

High

1031651

Q9VDI1
LD46328p

2

0

High-throughput

0.298

High

1031660

Q9VRQ4
LD47944p

2

0

High-throughput

0.298

High

1031663

CLIC
Chloride intracellular channel Clic

2

0

High-throughput

0.298

High

1031654

INO80
Chromatin-remodeling ATPase INO80

1

0

High-throughput

0.253

Low

55062

A1Z921
Frazzled, isoform B

1

0

Small-scale

0.249

Low

874635

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.249

Low

1031641

Q7K0P0
Juvenile hormone-inducible protein 26

1

0

High-throughput

0.249

Low

1031642

Q7K4C2
LD46713p

1

0

High-throughput

0.249

Low

1031643

Q7K4C7
choline-phosphate cytidylyltransferase

1

0

High-throughput

0.249

Low

1031648

CARME
Carnosine N-methyltransferase unmet

1

0

High-throughput

0.249

Low

1031653

Q9VDT1
Short-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

1031640

Q7JUM3
phosphatidylinositol N-acetylglucosaminyltransferase

1

0

High-throughput

0.232

Low

1031647

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.232

Low

1031649

Q9V3C2
LD47384p

1

0

High-throughput

0.232

Low

1031652

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.232

Low

1031657

Q9VIE7
GMP synthase

1

0

High-throughput

0.232

Low

1031658

CP310
Probable cytochrome P450 310a1

1

0

High-throughput

0.232

Low

1031659

Q9VQ06
AT26258p

1

0

High-throughput

0.232

Low

1031661

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.232

Low

1031662

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.232

Low

1031665

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.232

Low

1031667

Q9W5W9
LD43541p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025