Protein: LCOR
Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2)

Gene: LCOR
Organism: Homo sapiens
Interactions: 226
UniProt ID: Q96JN0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001222 - transcription corepressor binding
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032557

CTBP1
C-terminal-binding protein 1

10

5

Small-scale

0.758

High

881256

CTBP2
C-terminal-binding protein 2

7

5

Small-scale

0.752

High

1080239

EZH2
Histone-lysine N-methyltransferase EZH2

5

5

High-throughput

0.706

High

198037

PHF1
PHD finger protein 1

3

2

High-throughput

0.667

High

1063559

SUZ12
Polycomb protein SUZ12

4

0

High-throughput

0.664

High

1271097

EZH1
Histone-lysine N-methyltransferase EZH1

3

5

High-throughput

0.662

High

1295495

HDAC6
Histone deacetylase 6

2

3

Small-scale

0.629

High

992697

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

2

High-throughput

0.628

High

997858

RBBP4
Histone-binding protein RBBP4

2

1

High-throughput

0.628

High

1295467

KLDC3
Kelch domain-containing protein 3

2

1

High-throughput

0.628

High

1295510

MTF2
Metal-response element-binding transcription factor 2

2

2

High-throughput

0.628

High

268226

EED
Polycomb protein EED

3

0

High-throughput

0.622

High

1134183

PHF19
PHD finger protein 19

2

2

High-throughput

0.611

High

1082615

MK14
Mitogen-activated protein kinase 14

2

0

High-throughput

0.602

High

1189274

POGZ
Pogo transposable element with ZNF domain

2

0

High-throughput

0.602

High

1268299

ZN516
Zinc finger protein 516

2

0

High-throughput

0.602

High

1273795

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

0

High-throughput

0.602

High

1083346

RBBP7
Histone-binding protein RBBP7

2

1

High-throughput

0.601

High

370213

ESR1
Estrogen receptor

1

2

Small-scale

0.586

High

518454

ADT3
ADP/ATP translocase 3

2

0

High-throughput

0.585

High

1286574

BIRC7
Baculoviral IAP repeat-containing protein 7

2

0

High-throughput

0.580

High

943413

TCPB
T-complex protein 1 subunit beta

2

1

High-throughput

0.578

High

177358

HDAC3
Histone deacetylase 3

1

2

Small-scale

0.561

High

1295464

KLF6
Krueppel-like factor 6

1

0

Small-scale

0.549

High

270697

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.541

High

415453

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.541

High

452471

PGFRB
Platelet-derived growth factor receptor beta

1

1

High-throughput

0.541

High

600208

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.541

High

809393

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.541

High

865072

TTC3
E3 ubiquitin-protein ligase TTC3

1

2

High-throughput

0.541

High

1056617

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

2

High-throughput

0.541

High

1123993

TNI3K
Serine/threonine-protein kinase TNNI3K

1

1

High-throughput

0.541

High

1272537

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

1295463

RANB9
Ran-binding protein 9

1

1

High-throughput

0.541

High

1295485

TBG2
Tubulin gamma-2 chain

1

1

High-throughput

0.541

High

843335

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.536

High

1174181

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

1

High-throughput

0.536

High

487682

ANDR
Androgen receptor

1

2

Small-scale

0.527

High

118780

AIP
AH receptor-interacting protein

1

0

High-throughput

0.518

High

132992

SDCB1
Syntenin-1

1

0

High-throughput

0.518

High

148095

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

0

High-throughput

0.518

High

181237

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.518

High

217199

EXTL3
Exostosin-like 3

1

0

High-throughput

0.518

High

262921

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.518

High

272245

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

0

High-throughput

0.518

High

297776

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.518

High

375993

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.518

High

378563

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.518

High

500857

CLUS
Clusterin

1

0

High-throughput

0.518

High

531242

EF2
Elongation factor 2

1

0

High-throughput

0.518

High

543057

GLNA
Glutamine synthetase

1

0

High-throughput

0.518

High

616071

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.518

High

641266

DNMT1
DNA

1

0

High-throughput

0.518

High

656516

PSB4
Proteasome subunit beta type-4

1

0

High-throughput

0.518

High

751773

GRP75
Stress-70 protein, mitochondrial

1

0

High-throughput

0.518

High

782213

UBA7
Ubiquitin-like modifier-activating enzyme 7

1

0

High-throughput

0.518

High

835492

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.518

High

842382

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.518

High

854122

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.518

High

891975

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.518

High

909914

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.518

High

972466

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

0

High-throughput

0.518

High

1023219

FLII
Protein flightless-1 homolog

1

0

High-throughput

0.518

High

1031583

ATM
Serine-protein kinase ATM

1

0

High-throughput

0.518

High

1050381

TTL12
Tubulin--tyrosine ligase-like protein 12

1

0

High-throughput

0.518

High

1053469

GAMT
Guanidinoacetate N-methyltransferase

1

0

High-throughput

0.518

High

1081889

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

High-throughput

0.518

High

1199130

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.518

High

1199787

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

0

High-throughput

0.518

High

1242920

ABCF1
ATP-binding cassette sub-family F member 1

1

0

High-throughput

0.518

High

1243305

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.518

High

1264358

THAP4
Peroxynitrite isomerase THAP4

1

0

High-throughput

0.518

High

1295465

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.518

High

1295470

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

0

High-throughput

0.518

High

1295472

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.518

High

1295473

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.518

High

1295474

TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1

1

0

High-throughput

0.518

High

1295479

TARA
TRIO and F-actin-binding protein

1

0

High-throughput

0.518

High

1295480

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

High-throughput

0.518

High

1295486

ZHANG
CREB/ATF bZIP transcription factor

1

0

High-throughput

0.518

High

1295490

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.518

High

1295501

SRGEF
Secretion-regulating guanine nucleotide exchange factor

1

0

High-throughput

0.518

High

1295502

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.518

High

1295514

CABIN
Calcineurin-binding protein cabin-1

1

0

High-throughput

0.518

High

57021

A2ABF9
Euchromatic histone lysine methyltransferase 2

1

2

High-throughput

0.515

High

1270249

RORB
Nuclear receptor ROR-beta

1

2

High-throughput

0.515

High

564996

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

727419

DEK
Protein DEK

1

0

High-throughput

0.513

High

948829

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

986967

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

1060873

IMB1
Importin subunit beta-1

1

0

High-throughput

0.513

High

1061207

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1087340

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1295468

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.513

High

1295469

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.513

High

1295478

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

1295491

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.513

High

1295498

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

High-throughput

0.513

High

1295509

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.513

High

509975

VDR
Vitamin D3 receptor

1

3

Small-scale

0.501

High

880803

HDAC4
Histone deacetylase 4

1

3

Small-scale

0.501

High

1038628

HDAC1
Histone deacetylase 1

1

2

Small-scale

0.501

High

254288

LRP4
Low-density lipoprotein receptor-related protein 4

1

2

High-throughput

0.494

High

259506

LRRN2
Leucine-rich repeat neuronal protein 2

1

1

High-throughput

0.494

High

302311

SC31A
Protein transport protein Sec31A

1

2

High-throughput

0.494

High

1138785

ATRN1
Attractin-like protein 1

1

1

High-throughput

0.494

High

1140702

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.494

High

1217628

NAV3
Neuron navigator 3

1

1

High-throughput

0.494

High

1295461

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.494

High

1295483

LRRC4
Leucine-rich repeat-containing protein 4

1

1

High-throughput

0.494

High

1295492

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

2

High-throughput

0.494

High

1295496

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

5

High-throughput

0.494

High

162118

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

0

High-throughput

0.493

High

770985

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.489

High

821363

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.489

High

1123355

Q58EY0
RAR related orphan receptor B isoform 1

1

2

High-throughput

0.481

High

62829

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

2

High-throughput

0.479

High

569968

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

631550

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

831592

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

980841

TLE3
Transducin-like enhancer protein 3

1

1

High-throughput

0.479

High

1027192

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

1244431

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

917754

H4
Histone H4

1

0

High-throughput

0.458

High

1016230

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1168989

AEBP2
Zinc finger protein AEBP2

1

0

High-throughput

0.458

High

1271537

JARD2
Protein Jumonji

1

0

High-throughput

0.458

High

1295500

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1295507

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1295508

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1295459

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

High-throughput

0.457

High

131491

IMA4
Importin subunit alpha-4

1

1

High-throughput

0.445

High

134949

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.445

High

1295481

WDR76
WD repeat-containing protein 76

1

1

High-throughput

0.445

High

1295484

CBX8
Chromobox protein homolog 8

1

2

High-throughput

0.445

High

1295503

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

1

High-throughput

0.445

High

597690

VATB2
V-type proton ATPase subunit B, brain isoform

1

1

High-throughput

0.439

High

967361

EWS
RNA-binding protein EWS

1

0

High-throughput

0.438

High

489201

H14
Histone H1.4

1

0

High-throughput

0.426

High

585125

TFEB
Transcription factor EB

1

0

High-throughput

0.426

High

722280

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.426

High

802700

CRK
Adapter molecule crk

1

0

High-throughput

0.426

High

921931

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

1086382

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.426

High

1243159

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

1295506

CDYL
Chromodomain Y-like protein

1

0

High-throughput

0.426

High

377593

GCR
Glucocorticoid receptor

1

2

Small-scale

0.408

High

1023766

TRAF1
TNF receptor-associated factor 1

3

0

High-throughput

0.352

High

674708

AMRP
Alpha-2-macroglobulin receptor-associated protein

2

0

High-throughput

0.328

High

1295476

ZY11B
Protein zyg-11 homolog B

2

0

High-throughput

0.328

High

1295512

ASB3
Ankyrin repeat and SOCS box protein 3

2

0

High-throughput

0.328

High

1245740

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

995138

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.299

High

124926

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.282

High

154629

TPP1
Tripeptidyl-peptidase 1

1

0

High-throughput

0.282

High

206515

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.282

High

266869

CAH11
Carbonic anhydrase-related protein 11

1

0

High-throughput

0.282

High

311276

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.282

High

364592

TRFE
Serotransferrin

1

0

High-throughput

0.282

High

380920

VWF
von Willebrand factor

1

0

High-throughput

0.282

High

398474

PPBT
Alkaline phosphatase, tissue-nonspecific isozyme

1

0

High-throughput

0.282

High

431265

CATB
Cathepsin B

1

0

High-throughput

0.282

High

441769

CFAH
Complement factor H

1

0

High-throughput

0.282

High

473783

PA24B
Cytosolic phospholipase A2 beta

1

0

High-throughput

0.282

High

513620

PYC
Pyruvate carboxylase, mitochondrial

1

0

High-throughput

0.282

High

572138

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.282

High

577055

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.282

High

606469

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.282

High

606926

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.282

High

678047

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.282

High

812884

RPGP1
Rap1 GTPase-activating protein 1

1

0

High-throughput

0.282

High

816302

GLIP1
Glioma pathogenesis-related protein 1

1

0

High-throughput

0.282

High

839383

GATM
Glycine amidinotransferase, mitochondrial

1

0

High-throughput

0.282

High

856912

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

0

High-throughput

0.282

High

885050

FBXW4
F-box/WD repeat-containing protein 4

1

0

High-throughput

0.282

High

921030

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.282

High

942021

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.282

High

942477

CNTP1
Contactin-associated protein 1

1

0

High-throughput

0.282

High

979828

FOLH1
Glutamate carboxypeptidase 2

1

0

High-throughput

0.282

High

993051

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.282

High

1013944

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.282

High

1018344

MERTK
Tyrosine-protein kinase Mer

1

0

High-throughput

0.282

High

1030916

KCAB2
Voltage-gated potassium channel subunit beta-2

1

0

High-throughput

0.282

High

1045579

ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

1

0

High-throughput

0.282

High

1051409

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.282

High

1054978

SPRL1
SPARC-like protein 1

1

0

High-throughput

0.282

High

1086985

KGUA
Guanylate kinase

1

0

High-throughput

0.282

High

1133323

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.282

High

1188479

GLUCM
D-glutamate cyclase, mitochondrial

1

0

High-throughput

0.282

High

1198868

ACOT1
Acyl-coenzyme A thioesterase 1

1

0

High-throughput

0.282

High

1223809

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.282

High

1223958

CHSS2
Chondroitin sulfate synthase 2

1

0

High-throughput

0.282

High

1235258

NGEF
Ephexin-1

1

0

High-throughput

0.282

High

1237184

F86B1
Putative protein N-methyltransferase FAM86B1

1

0

High-throughput

0.282

High

1243189

DEN6B
Protein DENND6B

1

0

High-throughput

0.282

High

1271385

NRCAM
Neuronal cell adhesion molecule

1

0

High-throughput

0.282

High

1285998

MOAP1
Modulator of apoptosis 1

1

0

High-throughput

0.282

High

1291253

STALP
AMSH-like protease

1

0

High-throughput

0.282

High

1295460

GD1L1
Ganglioside-induced differentiation-associated protein 1-like 1

1

0

High-throughput

0.282

High

1295462

FMNL2
Formin-like protein 2

1

0

High-throughput

0.282

High

1295471

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.282

High

1295475

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.282

High

1295477

CYRIA
CYFIP-related Rac1 interactor A

1

0

High-throughput

0.282

High

1295487

MTMRA
Myotubularin-related protein 10

1

0

High-throughput

0.282

High

1295488

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.282

High

1295493

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

0

High-throughput

0.282

High

1295494

STX18
Syntaxin-18

1

0

High-throughput

0.282

High

1295497

PKHB1
Pleckstrin homology domain-containing family B member 1

1

0

High-throughput

0.282

High

1295499

IF172
Intraflagellar transport protein 172 homolog

1

0

High-throughput

0.282

High

1295504

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.282

High

1295505

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

0

High-throughput

0.282

High

1295513

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.282

High

660667

GRN
Progranulin

1

0

High-throughput

0.279

Low

895012

RAB4B
Ras-related protein Rab-4B

1

0

High-throughput

0.279

Low

922080

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.279

Low

1237349

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.279

Low

1295489

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.279

Low

323005

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

354538

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.238

Low

484515

ECE2
Endothelin-converting enzyme 2

1

0

High-throughput

0.238

Low

1137774

OBSCN
Obscurin

1

0

High-throughput

0.232

Low

1169423

NBEL2
Neurobeachin-like protein 2

1

0

High-throughput

0.232

Low

1198984

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low

1295466

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.232

Low

1295482

RPF1
Ribosome production factor 1

1

0

High-throughput

0.232

Low

1295511

PRC2C
Protein PRRC2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024