Protein: TP53B
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)

Gene: TP53B, Tp53bp1
Organism: Mus musculus
Interactions: 23
UniProt ID: P70399

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000781 - chromosome, telomeric region
GO:0002039 - p53 binding
GO:0003684 - damaged DNA binding
GO:0003712 - transcription coregulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

382466

P53
Cellular tumor antigen p53

1

11

Small-scale

0.646

High

1000355

MDC1
Mediator of DNA damage checkpoint protein 1

1

19

Small-scale

0.618

High

1000357

PAXI1
PAX-interacting protein 1

1

13

Small-scale

0.618

High

104410

F6M2J9
Nuclear receptor coactivator-6 beta

1

9

Small-scale

0.561

High

1000360

RN168
E3 ubiquitin-protein ligase RNF168

1

3

Small-scale

0.561

High

1000352

TNIK
Traf2 and NCK-interacting protein kinase

1

6

High-throughput

0.536

High

1000354

HERC2
E3 ubiquitin-protein ligase HERC2

1

10

High-throughput

0.536

High

1000356

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.536

High

1000358

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

High-throughput

0.536

High

1000361

MYOME
Myomegalin

1

6

High-throughput

0.536

High

1000364

TSC1
Hamartin

1

11

High-throughput

0.536

High

236570

ITB3
Integrin beta-3

1

7

High-throughput

0.501

High

629227

PO5F1
POU domain, class 5, transcription factor 1

1

5

High-throughput

0.479

High

771461

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

4

High-throughput

0.479

High

1000362

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.479

High

1000363

ARRB1
Beta-arrestin-1

1

5

Small-scale

0.479

High

1000365

CAF1A
Chromatin assembly factor 1 subunit A

1

10

High-throughput

0.479

High

1000366

MECP2
Methyl-CpG-binding protein 2

1

16

Small-scale

0.479

High

59026

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

7

Small-scale

0.470

High

777860

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.445

High

104506

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.437

High

1000353

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

High-throughput

0.407

High

1000359

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025