Protein: PRP8
Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8)

Gene: PRP8, Prpf8
Organism: Mus musculus
Interactions: 19
UniProt ID: Q99PV0

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005682 - U5 snRNP
GO:0008237 - metallopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1362610

EED
Polycomb protein EED

1

6

High-throughput

0.665

High

236632

ITB3
Integrin beta-3

1

1

High-throughput

0.501

High

586148

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.479

High

873042

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

928000

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

966076

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.479

High

1282456

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

1408997

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

478556

ITB1
Integrin beta-1

1

2

High-throughput

0.457

High

1231069

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.445

High

1408998

MECP2
Methyl-CpG-binding protein 2

1

1

Small-scale

0.445

High

1298335

MT21E
Protein-lysine methyltransferase METTL21E

1

1

High-throughput

0.437

High

59297

MEIOC
Meiosis-specific coiled-coil domain-containing protein MEIOC

1

0

Small-scale

0.426

High

1354108

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.426

High

1408603

CDK9
Cyclin-dependent kinase 9

1

0

Small-scale

0.426

High

398935

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

1317622

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

1188922

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.232

Low

1204318

MEIKN
Meiosis-specific kinetochore protein

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025