Protein: TYDP1
Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)

Gene: TYDP1, TDP1
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9NUW8

Gene Ontology (top 5):
GO:0000012 - single strand break repair
GO:0003690 - double-stranded DNA binding
GO:0003697 - single-stranded DNA binding
GO:0004527 - exonuclease activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

417842

DPOLB
DNA polymerase beta

4

0

High-throughput

0.670

High

836789

DNLI3
DNA ligase 3

4

0

Small-scale

0.670

High

579746

XRCC1
DNA repair protein XRCC1

4

0

Small-scale

0.664

High

1218136

APLF
Aprataxin and PNK-like factor

3

0

High-throughput

0.638

High

822388

KC1D
Casein kinase I isoform delta

2

0

High-throughput

0.602

High

853490

IMA1
Importin subunit alpha-1

2

0

High-throughput

0.595

High

834677

NU153
Nuclear pore complex protein Nup153

2

0

High-throughput

0.585

High

455923

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.536

High

850210

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.513

High

996923

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1187475

APTX
Aprataxin

1

0

High-throughput

0.513

High

1253304

POC1B
POC1 centriolar protein homolog B

1

0

High-throughput

0.513

High

1346242

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.513

High

764425

FEN1
Flap endonuclease 1

1

0

High-throughput

0.493

High

59955

A4FUJ8
MKL1 protein

1

0

High-throughput

0.493

High

278169

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.493

High

803772

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

997473

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.493

High

1075012

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.493

High

1169193

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.493

High

1216895

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.493

High

1233227

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.493

High

1317618

LDH6B
L-lactate dehydrogenase A-like 6B

1

0

High-throughput

0.493

High

1333319

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.493

High

1345285

RASF1
Ras association domain-containing protein 1

1

0

High-throughput

0.493

High

476451

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

153808

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.458

High

548130

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

0

Small-scale

0.458

High

652387

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

918723

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

986994

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1031622

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.458

High

1171931

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1345072

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.458

High

1132646

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.426

High

1346241

TRI33
E3 ubiquitin-protein ligase TRIM33

1

0

Small-scale

0.426

High

1016745

CETN1
Centrin-1

2

0

High-throughput

0.328

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024