Interactor 1: IRS2 (P81122)
Insulin receptor substrate 2 (IRS-2) (4PS)
Gene: IRS2

Interactor 2: PHIP (Q8VDD9)
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (Neuronal differentiation-related protein) (NDRP) (WD repeat-containing protein 11)
Gene: PHIP

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11018022
Identification Methods coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~WD40
Common GO terms GO:0008283 - cell population proliferation
GO:0008284 - positive regulation of cell population proliferation
GO:0008286 - insulin receptor signaling pathway
GO:0044342 - type B pancreatic cell proliferation
GO:1904692 - positive regulation of type B pancreatic cell proliferation
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1321
Mm

1 1821
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Last updated: 15 Jul 2024