Interactor 1: IRS2 (P81122)
Insulin receptor substrate 2 (IRS-2) (4PS)
Gene: IRS2
Interactor 2: PHIP (Q8VDD9)
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (Neuronal differentiation-related protein) (NDRP) (WD repeat-containing protein 11)
Gene: PHIP
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11018022 |
Identification Methods | coimmunoprecipitation |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PH~WD40 |
Common GO terms | GO:0008283 - cell population proliferation GO:0008284 - positive regulation of cell population proliferation GO:0008286 - insulin receptor signaling pathway GO:0044342 - type B pancreatic cell proliferation GO:1904692 - positive regulation of type B pancreatic cell proliferation |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024