HitPredict

Interactor 1: ALX4 (O35137)
Homeobox protein aristaless-like 4 (ALX-4)
Gene: ALX4

Interactor 2: TLE6 (Q9WVB3)
Transducin-like enhancer protein 6 (Groucho-related protein 6)
Gene: TLE6

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 399 Mm			1 581
+	Mm
		478358 HXD3_MOUSE (8-364): 1.33e-40: 150: 15.93		TLE6_MOUSE (1-581): 2.06e-128: 390: 100.00
+	Mm
		724909 HXA2_MOUSE (69-375): 7.83e-34: 131: 19.87		TLE6_MOUSE (1-581): 2.06e-128: 390: 100.00
+	Hs
		877510 LHX1_HUMAN (150-382): 2.91e-38: 144: 27.66		TLE1_HUMAN (112-581): 2.88e-105: 335: 25.00
+	Hs
		1047831 ISX_HUMAN (160-383): 5.01e-38: 139: 28.44		TLE1_HUMAN (112-581): 2.88e-105: 335: 25.00
+	Hs
		1047983 ISX_HUMAN (160-383): 5.01e-38: 139: 28.44		TLE3_HUMAN (278-581): 7.11e-102: 327: 33.44
+	Hs
		662215 PAX7_HUMAN (185-384): 3.64e-30: 123: 30.48		TLE1_HUMAN (112-581): 2.88e-105: 335: 25.00
+	Hs
		685162 PAX6_HUMAN (123-379): 3.67e-30: 122: 24.81		TLE1_HUMAN (112-581): 2.88e-105: 335: 25.00
+	Hs
		662216 PAX7_HUMAN (185-384): 3.64e-30: 123: 30.48		TLE3_HUMAN (278-581): 7.11e-102: 327: 33.44
+	Hs
		685163 PAX6_HUMAN (123-379): 3.67e-30: 122: 24.81		TLE3_HUMAN (278-581): 7.11e-102: 327: 33.44
+	Ce
		146025 UNC4_CAEEL (149-351): 2.07e-32: 124: 26.11		UNC37_CAEEL (180-581): 1.7e-94: 303: 24.11
+	Hs
		1048161 ISX_HUMAN (160-383): 5.01e-38: 139: 28.44		TLE4_HUMAN (92-581): 7.25e-81: 271: 25.46
+	Hs
		662217 PAX7_HUMAN (185-384): 3.64e-30: 123: 30.48		TLE4_HUMAN (92-581): 7.25e-81: 271: 25.46
+	Mm
		666052 PAX3_MOUSE (176-379): 1.28e-30: 124: 28.97		TLE4_MOUSE (92-581): 1.12e-80: 270: 25.46
+	Hs
		685164 PAX6_HUMAN (123-379): 3.67e-30: 122: 24.81		TLE4_HUMAN (92-581): 7.25e-81: 271: 25.46
+	Hs
		851810 NKX21_HUMAN (24-374): 1.27e-38: 144: 20.17		TBL1R_HUMAN (201-499): 1.17e-57: 203: 11.92
+	Hs
		261365 PAX7_HUMAN (185-384): 3.64e-30: 123: 30.48		TBL1X_HUMAN (143-499): 2.39e-55: 198: 10.45
+	Hs
		261369 PAX6_HUMAN (123-379): 3.67e-30: 122: 24.81		TBL1X_HUMAN (143-499): 2.39e-55: 198: 10.45
+	Hs
		965184 PITX2_HUMAN (175-393): 6.11e-33: 127: 28.39		WDR5_HUMAN (424-579): 2.81e-50: 178: 16.15
+	Hs
		662211 PAX7_HUMAN (185-384): 3.64e-30: 123: 30.48		WDR5_HUMAN (424-579): 2.81e-50: 178: 16.15
+	Mm
		866404 PAX7_MOUSE (185-384): 3.23e-29: 120: 30.95		WDR5_MOUSE (424-579): 2.81e-50: 178: 16.15