Protein: DCAF6
DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)

Gene: DCAF6
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q58WW2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082217

DDB1
DNA damage-binding protein 1

7

20

Small-scale

0.965

High

1123631

WDFY3
WD repeat and FYVE domain-containing protein 3

2

19

High-throughput

0.811

High

1123616

DCAF6
DDB1- and CUL4-associated factor 6

2

17

Small-scale

0.754

High

1043032

CUL4A
Cullin-4A

8

20

Small-scale

0.745

High

1043396

CUL4B
Cullin-4B

5

20

Small-scale

0.716

High

795637

MAGA1
Melanoma-associated antigen 1

4

6

High-throughput

0.694

High

1123677

PIHD1
PIH1 domain-containing protein 1

4

4

High-throughput

0.694

High

1123694

NR2E1
Nuclear receptor subfamily 2 group E member 1

4

17

High-throughput

0.694

High

487493

ANDR
Androgen receptor

3

20

Small-scale

0.669

High

795820

MAGA4
Melanoma-associated antigen 4

3

6

High-throughput

0.667

High

1123630

YAF2
YY1-associated factor 2

3

3

High-throughput

0.667

High

1123647

TET5A
Terminal nucleotidyltransferase 5A

3

1

High-throughput

0.667

High

1123655

MDFI
MyoD family inhibitor

3

1

High-throughput

0.653

High

1123685

VPS28
Vacuolar protein sorting-associated protein 28 homolog

3

0

High-throughput

0.638

High

636350

DNJB1
DnaJ homolog subfamily B member 1

2

8

High-throughput

0.628

High

377380

GCR
Glucocorticoid receptor

2

20

Small-scale

0.624

High

296045

MTA2
Metastasis-associated protein MTA2

1

4

High-throughput

0.618

High

895803

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

3

High-throughput

0.618

High

896120

UBC12
NEDD8-conjugating enzyme Ubc12

1

7

High-throughput

0.618

High

903281

WDR5
WD repeat-containing protein 5

1

19

High-throughput

0.618

High

980693

TLE2
Transducin-like enhancer protein 2

1

19

High-throughput

0.618

High

983382

DYN1
Dynamin-1

1

1

High-throughput

0.618

High

1028003

ERCC8
DNA excision repair protein ERCC-8

1

18

High-throughput

0.618

High

1117747

Q4LE69
1-phosphatidylinositol 4-kinase

1

4

High-throughput

0.618

High

1123633

WDTC1
WD and tetratricopeptide repeats protein 1

1

18

High-throughput

0.618

High

1123641

PHIP
PH-interacting protein

1

19

High-throughput

0.618

High

1123645

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

High-throughput

0.618

High

1123649

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

High-throughput

0.618

High

1123656

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

20

High-throughput

0.618

High

1123659

NUP85
Nuclear pore complex protein Nup85

1

1

High-throughput

0.618

High

1123665

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

19

High-throughput

0.618

High

1123632

CLIP4
CAP-Gly domain-containing linker protein 4

2

10

High-throughput

0.614

High

669387

EF1D
Elongation factor 1-delta

2

2

High-throughput

0.611

High

897259

CSN2
COP9 signalosome complex subunit 2

2

11

High-throughput

0.611

High

1123674

CABP2
Calcium-binding protein 2

2

2

High-throughput

0.611

High

328292

BMP15
Bone morphogenetic protein 15

3

2

High-throughput

0.609

High

1123662

CABP8
Calcium-binding protein 8

3

4

High-throughput

0.604

High

1123668

PAAT
ATPase PAAT

2

0

High-throughput

0.602

High

1123663

TRI55
Tripartite motif-containing protein 55

2

20

High-throughput

0.586

High

311084

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.586

High

361222

TNNC2
Troponin C, skeletal muscle

2

0

High-throughput

0.585

High

123258

CBX4
E3 SUMO-protein ligase CBX4

2

14

High-throughput

0.584

High

598155

FLNA
Filamin-A

2

15

High-throughput

0.584

High

1123660

DDA1
DET1- and DDB1-associated protein 1

2

6

High-throughput

0.584

High

881192

CTBP2
C-terminal-binding protein 2

1

8

High-throughput

0.561

High

1032448

CTBP1
C-terminal-binding protein 1

1

8

High-throughput

0.561

High

1032973

PLD1
Phospholipase D1

1

1

High-throughput

0.553

High

1123683

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

1

Small-scale

0.552

High

245987

PFD1
Prefoldin subunit 1

1

5

High-throughput

0.536

High

420783

CALCA
Calcitonin gene-related peptide 1

1

1

High-throughput

0.536

High

515454

CDK4
Cyclin-dependent kinase 4

1

10

High-throughput

0.536

High

885110

CABP4
Calcium-binding protein 4

1

2

High-throughput

0.536

High

957189

DAB2
Disabled homolog 2

1

5

High-throughput

0.536

High

1024170

CSN1
COP9 signalosome complex subunit 1

1

11

High-throughput

0.536

High

1055053

KT33B
Keratin, type I cuticular Ha3-II

1

9

High-throughput

0.536

High

1059157

CBX2
Chromobox protein homolog 2

1

14

High-throughput

0.536

High

1123628

FMNL3
Formin-like protein 3

1

1

High-throughput

0.536

High

1123654

CSN8
COP9 signalosome complex subunit 8

1

2

High-throughput

0.536

High

1123657

MYL10
Myosin regulatory light chain 10

1

1

High-throughput

0.536

High

1123664

UCK2
Uridine-cytidine kinase 2

1

2

High-throughput

0.536

High

1123676

MYO5C
Unconventional myosin-Vc

1

5

High-throughput

0.536

High

1123686

ING1
Inhibitor of growth protein 1

1

9

High-throughput

0.536

High

1123689

CSN3
COP9 signalosome complex subunit 3

1

11

High-throughput

0.536

High

718915

PHB1
Prohibitin 1

1

10

High-throughput

0.515

High

1123634

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

7

High-throughput

0.515

High

435955

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.513

High

614207

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.513

High

739733

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

1123646

TRI63
E3 ubiquitin-protein ligase TRIM63

1

18

High-throughput

0.508

High

279245

LYZL6
Lysozyme-like protein 6

1

1

High-throughput

0.489

High

664165

NEC1
Neuroendocrine convertase 1

1

3

High-throughput

0.489

High

709254

GALNS
N-acetylgalactosamine-6-sulfatase

1

2

High-throughput

0.489

High

793783

CATO
Cathepsin O

1

1

High-throughput

0.489

High

1037559

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

1

High-throughput

0.489

High

1123638

DQX1
ATP-dependent RNA helicase DQX1

1

8

High-throughput

0.489

High

1123648

LOXL4
Lysyl oxidase homolog 4

1

1

High-throughput

0.489

High

1123682

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.489

High

1123688

PA2GD
Group IID secretory phospholipase A2

1

1

High-throughput

0.489

High

1123692

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

2

High-throughput

0.489

High

63009

HMX3
Homeobox protein HMX3

1

3

High-throughput

0.479

High

118746

AIP
AH receptor-interacting protein

1

15

High-throughput

0.479

High

136024

ACACB
Acetyl-CoA carboxylase 2

1

16

High-throughput

0.479

High

146234

ARI1A
AT-rich interactive domain-containing protein 1A

1

11

High-throughput

0.479

High

162824

XPO1
Exportin-1

1

19

High-throughput

0.479

High

171629

PFD6
Prefoldin subunit 6

1

8

High-throughput

0.479

High

260080

VATG1
V-type proton ATPase subunit G 1

1

1

High-throughput

0.479

High

317978

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

7

High-throughput

0.479

High

323418

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.479

High

398359

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.479

High

417732

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.479

High

426524

KLK3
Prostate-specific antigen

1

3

High-throughput

0.479

High

426662

H10
Histone H1.0

1

1

High-throughput

0.479

High

435114

SP1
Transcription factor Sp1

1

3

Small-scale

0.479

High

449282

LEG1
Galectin-1

1

7

High-throughput

0.479

High

489081

H14
Histone H1.4

1

11

High-throughput

0.479

High

495542

THIO
Thioredoxin

1

8

High-throughput

0.479

High

513584

PYC
Pyruvate carboxylase, mitochondrial

1

16

High-throughput

0.479

High

522620

MYH7
Myosin-7

1

3

High-throughput

0.479

High

531583

K2C5
Keratin, type II cytoskeletal 5

1

6

High-throughput

0.479

High

542347

PLAK
Junction plakoglobin

1

13

High-throughput

0.479

High

549897

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

6

High-throughput

0.479

High

551728

DESP
Desmoplakin

1

20

High-throughput

0.479

High

573292

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.479

High

639760

IKBA
NF-kappa-B inhibitor alpha

1

9

High-throughput

0.479

High

814966

LEG7
Galectin-7

1

7

High-throughput

0.479

High

821245

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.479

High

835393

GSK3A
Glycogen synthase kinase-3 alpha

1

8

High-throughput

0.479

High

836650

GUAA
GMP synthase [glutamine-hydrolyzing]

1

3

High-throughput

0.479

High

853616

IMA5
Importin subunit alpha-5

1

3

High-throughput

0.479

High

862052

DAPK1
Death-associated protein kinase 1

1

11

High-throughput

0.479

High

863778

LIMK1
LIM domain kinase 1

1

13

High-throughput

0.479

High

882920

RBM11
Splicing regulator RBM11

1

13

High-throughput

0.479

High

901680

PFD3
Prefoldin subunit 3

1

9

High-throughput

0.479

High

924613

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.479

High

942355

DLG4
Disks large homolog 4

1

1

High-throughput

0.479

High

959171

METK1
S-adenosylmethionine synthase isoform type-1

1

2

High-throughput

0.479

High

964000

SRSF2
Serine/arginine-rich splicing factor 2

1

7

High-throughput

0.479

High

968257

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

2

High-throughput

0.479

High

970785

DSG1
Desmoglein-1

1

4

High-throughput

0.479

High

972522

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

15

High-throughput

0.479

High

979310

UBXN1
UBX domain-containing protein 1

1

2

High-throughput

0.479

High

981122

ACVR1
Activin receptor type-1

1

4

High-throughput

0.479

High

984268

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

2

High-throughput

0.479

High

987978

RING1
E3 ubiquitin-protein ligase RING1

1

20

High-throughput

0.479

High

1024023

ACACA
Acetyl-CoA carboxylase 1

1

16

High-throughput

0.479

High

1029209

GRM1
Metabotropic glutamate receptor 1

1

2

High-throughput

0.479

High

1033658

IKZF1
DNA-binding protein Ikaros

1

7

High-throughput

0.479

High

1038883

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

3

High-throughput

0.479

High

1049222

KEAP1
Kelch-like ECH-associated protein 1

1

3

High-throughput

0.479

High

1056855

MDC1
Mediator of DNA damage checkpoint protein 1

1

20

High-throughput

0.479

High

1059659

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

12

High-throughput

0.479

High

1076158

MED1
Mediator of RNA polymerase II transcription subunit 1

1

9

High-throughput

0.479

High

1083213

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

5

High-throughput

0.479

High

1083854

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

1084294

SRSF7
Serine/arginine-rich splicing factor 7

1

18

High-throughput

0.479

High

1089455

KCD19
BTB/POZ domain-containing protein KCTD19

1

1

High-throughput

0.479

High

1123618

PCID2
PCI domain-containing protein 2

1

7

High-throughput

0.479

High

1123619

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.479

High

1123623

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

11

High-throughput

0.479

High

1123624

DCNL2
DCN1-like protein 2

1

1

High-throughput

0.479

High

1123627

NUDC3
NudC domain-containing protein 3

1

16

High-throughput

0.479

High

1123637

CALL6
Calmodulin-like protein 6

1

1

High-throughput

0.479

High

1123639

NUDC2
NudC domain-containing protein 2

1

16

High-throughput

0.479

High

1123642

HXB13
Homeobox protein Hox-B13

1

2

High-throughput

0.479

High

1123643

GLMN
Glomulin

1

2

High-throughput

0.479

High

1123644

KAT5
Histone acetyltransferase KAT5

1

6

High-throughput

0.479

High

1123650

SNX27
Sorting nexin-27

1

4

High-throughput

0.479

High

1123651

NSUN5
28S rRNA

1

4

High-throughput

0.479

High

1123652

DCE1
Glutamate decarboxylase 1

1

1

High-throughput

0.479

High

1123653

PFD5
Prefoldin subunit 5

1

8

High-throughput

0.479

High

1123670

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

2

High-throughput

0.479

High

1123671

MOV10
Helicase MOV-10

1

5

High-throughput

0.479

High

1123672

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

8

High-throughput

0.479

High

1123673

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

15

High-throughput

0.479

High

1123675

PFD4
Prefoldin subunit 4

1

6

High-throughput

0.479

High

1123679

AKA7G
A-kinase anchor protein 7 isoform gamma

1

1

High-throughput

0.479

High

1123680

NLK
Serine/threonine-protein kinase NLK

1

8

High-throughput

0.479

High

1123681

CSN7A
COP9 signalosome complex subunit 7a

1

7

High-throughput

0.479

High

1123684

PFD2
Prefoldin subunit 2

1

6

High-throughput

0.479

High

1123687

BRPF3
Bromodomain and PHD finger-containing protein 3

1

9

High-throughput

0.479

High

1123691

CDYL
Chromodomain Y-like protein

1

5

High-throughput

0.479

High

175463

PMM2
Phosphomannomutase 2

1

0

High-throughput

0.458

High

316432

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.458

High

417512

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.458

High

484375

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

575467

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

667692

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.458

High

781555

CETN2
Centrin-2

1

0

High-throughput

0.458

High

819637

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.458

High

927824

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.458

High

1039425

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

0

High-throughput

0.458

High

1088006

DUS6
Dual specificity protein phosphatase 6

1

0

High-throughput

0.458

High

1123620

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

High-throughput

0.458

High

1123621

CPZIP
CapZ-interacting protein

1

0

High-throughput

0.458

High

1123635

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.458

High

1123678

DDIT4
DNA damage-inducible transcript 4 protein

1

0

High-throughput

0.458

High

1123693

ZFP30
Zinc finger protein 30 homolog

1

0

High-throughput

0.458

High

1123669

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

8

High-throughput

0.457

High

402115

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

1123625

CSN6
COP9 signalosome complex subunit 6

1

8

High-throughput

0.445

High

500804

CLUS
Clusterin

1

0

High-throughput

0.438

High

1123629

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

200743

ADCY6
Adenylate cyclase type 6

1

1

High-throughput

0.437

High

317555

ADCY5
Adenylate cyclase type 5

1

1

High-throughput

0.437

High

329766

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.437

High

384956

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

433156

LAMB1
Laminin subunit beta-1

1

3

High-throughput

0.437

High

506304

MBL2
Mannose-binding protein C

1

2

High-throughput

0.437

High

671460

ECHM
Enoyl-CoA hydratase, mitochondrial

1

4

High-throughput

0.437

High

786701

GRIA1
Glutamate receptor 1

1

1

High-throughput

0.437

High

822758

SL9A3
Sodium/hydrogen exchanger 3

1

1

High-throughput

0.437

High

1058635

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

2

High-throughput

0.437

High

1123658

SPON2
Spondin-2

1

1

High-throughput

0.437

High

1123666

TRPV6
Transient receptor potential cation channel subfamily V member 6

1

1

High-throughput

0.437

High

1123667

KCNN2
Small conductance calcium-activated potassium channel protein 2

1

3

High-throughput

0.437

High

1123690

ATS8
A disintegrin and metalloproteinase with thrombospondin motifs 8

1

1

High-throughput

0.437

High

211306

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

1

High-throughput

0.407

High

351794

CALC
Calcitonin [Cleaved into: Calcitonin; Katacalcin

1

1

High-throughput

0.407

High

1123661

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

0

High-throughput

0.347

High

1123622

FAH2B
Fumarylacetoacetate hydrolase domain-containing protein 2B

1

0

High-throughput

0.279

Low

1123626

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

1123636

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.279

Low

1123640

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

528349

SCG2
Secretogranin-2

1

0

High-throughput

0.269

Low

888259

MYPR
Myelin proteolipid protein

1

0

High-throughput

0.249

Low

1123617

PIGG
GPI ethanolamine phosphate transferase 2

1

0

High-throughput

0.249

Low

886292

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024