Protein: MFSD6
Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog)

Gene: MFSD6
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q6ZSS7

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0042590 - antigen processing and presentation of exogenous peptide antigen via MHC class I

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

706032

CXB2
Gap junction beta-2 protein

2

1

High-throughput

0.606

High

870736

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.606

High

1134114

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.606

High

1185978

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.606

High

74170

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.580

High

331477

APOL3
Apolipoprotein L3

2

0

High-throughput

0.580

High

360022

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.580

High

549807

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

958567

TM258
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258

2

0

High-throughput

0.580

High

1158656

LY6E
Lymphocyte antigen 6E

2

0

High-throughput

0.580

High

1159474

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

1187395

SHSL1
Protein shisa-like-1

2

0

High-throughput

0.580

High

1216434

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

1254178

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

1254182

CS018
Uncharacterized protein C19orf18

2

0

High-throughput

0.580

High

1254183

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.580

High

1254184

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

1254185

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

1254186

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.580

High

1254187

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1254188

PD1L2
Programmed cell death 1 ligand 2

2

0

High-throughput

0.580

High

1254193

SYNG1
Synapse differentiation-inducing gene protein 1

2

0

High-throughput

0.580

High

1254195

S39A2
Zinc transporter ZIP2

2

0

High-throughput

0.580

High

1254200

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

1254203

SELK
Selenoprotein K

2

0

High-throughput

0.580

High

337756

SGPL1
Sphingosine-1-phosphate lyase 1

2

1

High-throughput

0.553

High

1242824

Q6P5T0
AQP7 protein

1

1

High-throughput

0.515

High

3410

A0A0S2Z4U3
Syndecan

1

0

High-throughput

0.493

High

188916

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.493

High

193422

GPR42
G-protein coupled receptor 42

1

0

High-throughput

0.493

High

155384

AQP7
Aquaporin-7

1

1

High-throughput

0.481

High

1254191

RHOJ
Rho-related GTP-binding protein RhoJ

1

1

High-throughput

0.479

High

779710

MOT8
Monocarboxylate transporter 8

1

0

High-throughput

0.460

High

466320

RHOC
Rho-related GTP-binding protein RhoC

1

0

High-throughput

0.458

High

321278

ERLN2
Erlin-2

1

1

High-throughput

0.445

High

178640

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.426

High

467269

MDR1
ATP-dependent translocase ABCB1

1

0

High-throughput

0.426

High

543225

UBL4A
Ubiquitin-like protein 4A

1

0

High-throughput

0.426

High

934225

BI1
Bax inhibitor 1

1

0

High-throughput

0.426

High

1112061

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.426

High

1236195

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1254180

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

0

High-throughput

0.426

High

1254181

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.426

High

1254194

NPAL2
NIPA-like protein 2

1

0

High-throughput

0.426

High

1254199

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.426

High

1254201

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.426

High

283284

ERLN1
Erlin-1

1

1

High-throughput

0.407

High

926794

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

1142858

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

1154993

ADIPO
Adiponectin

2

0

High-throughput

0.316

High

1216321

MFS4B
Sodium-dependent glucose transporter 1

2

0

High-throughput

0.316

High

1254179

STX12
Syntaxin-12

2

0

High-throughput

0.316

High

1254190

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

2

0

High-throughput

0.316

High

1254198

TM242
Transmembrane protein 242

2

0

High-throughput

0.316

High

1207529

F209A
Protein FAM209A

1

0

High-throughput

0.251

Low

81717

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

0

High-throughput

0.232

Low

230042

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

0

High-throughput

0.232

Low

343972

HS74L
Heat shock 70 kDa protein 4L

1

0

High-throughput

0.232

Low

855892

CRKL
Crk-like protein

1

0

High-throughput

0.232

Low

882327

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.232

Low

1053487

ITIH3
Inter-alpha-trypsin inhibitor heavy chain H3

1

0

High-throughput

0.232

Low

1254189

THUM3
tRNA

1

0

High-throughput

0.232

Low

1254192

DCTP1
dCTP pyrophosphatase 1

1

0

High-throughput

0.232

Low

1254196

FBX6
F-box only protein 6

1

0

High-throughput

0.232

Low

1254197

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.232

Low

1254202

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025