Protein: HEM2
Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)

Gene: HEM2, ALAD
Organism: Homo sapiens
Interactions: 19
UniProt ID: P13716

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0003824 - catalytic activity
GO:0004655 - porphobilinogen synthase activity
GO:0005576 - extracellular region
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567748

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.602

High

567749

CNN2
Calponin-2

2

0

High-throughput

0.585

High

292533

RENR
Renin receptor

1

0

High-throughput

0.513

High

420238

IFNA4
Interferon alpha-4

1

0

High-throughput

0.513

High

567738

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

567739

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

567743

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.513

High

567747

DAA19
Dynein axonemal assembly factor 19

1

0

High-throughput

0.513

High

567750

PLK2
Serine/threonine-protein kinase PLK2

1

0

High-throughput

0.513

High

567746

GRP2
RAS guanyl-releasing protein 2

1

0

High-throughput

0.493

High

567740

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

567745

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

404647

PRIO
Major prion protein

1

0

High-throughput

0.426

High

567751

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.426

High

64171

ARG35
Rho guanine nucleotide exchange factor 35

3

0

High-throughput

0.345

High

105238

APRIO
Alternative prion protein

2

0

High-throughput

0.305

High

567741

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

567742

GMFB
Glia maturation factor beta

1

0

High-throughput

0.279

Low

567744

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025