Protein: ERD2
ER lumen protein-retaining receptor

Gene: ERD2, KdelR
Organism: Drosophila melanogaster
Interactions: 135
UniProt ID: O76767

Gene Ontology (top 5):
GO:0005046 - KDEL sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005801 - cis-Golgi network
GO:0006621 - protein retention in ER lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

197202

RAB6
Ras-related protein Rab6

2

2

High-throughput

0.571

High

197923

SURF4
Surfeit locus protein 4 homolog

2

2

High-throughput

0.571

High

304103

RAB7
Ras-related protein Rab7

2

5

High-throughput

0.571

High

304182

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

5

High-throughput

0.571

High

304186

ARF4
ADP ribosylation factor 4

2

3

High-throughput

0.571

High

304191

ARF1
ADP-ribosylation factor 1

2

3

High-throughput

0.571

High

304232

RAB5
Ras-related protein Rab5

2

2

High-throughput

0.571

High

304255

ARL8
ADP-ribosylation factor-like protein 8

2

5

High-throughput

0.571

High

197036

O18332
FI01544p

2

0

High-throughput

0.547

High

304204

Q6NR46
Serine palmitoyltransferase 1

2

0

High-throughput

0.547

High

304223

Q8STG9
DSec61alpha

2

0

High-throughput

0.547

High

304238

KRH2
Krueppel homolog 2

2

0

High-throughput

0.547

High

304247

Q9VBU5
3-dehydrosphinganine reductase

2

0

High-throughput

0.547

High

304279

Q9VUZ0
Translocon-associated protein subunit beta

2

0

High-throughput

0.547

High

304286

Q9VXG0
Cell division cycle 50, isoform A

2

0

High-throughput

0.547

High

304288

Q9VZL3
very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.547

High

304294

Q9W3N1
RH59310p

2

0

High-throughput

0.547

High

304178

O96692
small monomeric GTPase

2

2

High-throughput

0.521

High

304198

DX39B
ATP-dependent RNA helicase WM6

2

1

High-throughput

0.521

High

304227

VDAC
Voltage-dependent anion-selective channel

2

2

High-throughput

0.521

High

304285

Q9VWL0
Mec2

2

1

High-throughput

0.521

High

304271

EXOC2
Exocyst complex component 2

1

1

High-throughput

0.508

High

52631

A1Z729
NADP-retinol dehydrogenase

1

3

High-throughput

0.479

High

94119

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

3

High-throughput

0.479

High

197133

RAB2
Ras-related protein Rab-2

1

1

High-throughput

0.479

High

304222

Q8MZG9
NADP-retinol dehydrogenase

1

3

High-throughput

0.479

High

304207

Q7JYX2
NADP-retinol dehydrogenase

1

3

High-throughput

0.445

High

304231

XPO1
Exportin-1

1

2

High-throughput

0.445

High

304259

Q9VK46
Protein YIPF

1

1

High-throughput

0.445

High

304295

Q9W3Q0
FI07418p

1

2

High-throughput

0.445

High

304218

Q8IN05
Liquid facets-Related, isoform D

1

2

High-throughput

0.439

High

304205

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

304212

Q7K3K5
LD22804p

1

1

High-throughput

0.437

High

304217

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.437

High

53663

A1Z843
Nodal modulator 3

1

0

High-throughput

0.426

High

55365

A1Z9E0
diacylglycerol cholinephosphotransferase

1

0

High-throughput

0.426

High

304210

JAGN
Protein jagunal

1

0

High-throughput

0.426

High

304213

Q7KLX3
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

304220

Q8IRR0
Cytochrome b5

1

0

High-throughput

0.426

High

304230

Q960D4
SD06560p

1

0

High-throughput

0.426

High

304243

Q9VAL7
Calnexin 99A, isoform A

1

0

High-throughput

0.426

High

304244

CISD2
CDGSH iron-sulfur domain protein

1

0

High-throughput

0.426

High

304246

Q9VAY2
Heat shock protein 83

1

0

High-throughput

0.426

High

304254

UNC50
Protein unc-50 homolog

1

0

High-throughput

0.426

High

304256

Q9VI53
LD44267p

1

0

High-throughput

0.426

High

304262

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

0

High-throughput

0.426

High

304264

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.426

High

304276

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.426

High

304290

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

304297

Q9W4N8
LD30122p

1

0

High-throughput

0.426

High

304250

Q9VD13
GH02671p

1

2

High-throughput

0.417

High

120912

M9PEG6
Zinc transporter 63C, isoform F

1

1

High-throughput

0.407

High

304180

RAP1
Ras-related protein Rap1

1

2

High-throughput

0.407

High

304181

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

5

High-throughput

0.407

High

304188

COPB
Coatomer subunit beta

1

1

High-throughput

0.407

High

304189

PRS4
26S proteasome regulatory subunit 4

1

4

High-throughput

0.407

High

304190

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

304192

ARL2
ADP-ribosylation factor-like protein 2

1

6

High-throughput

0.407

High

304193

Q0E8E8
Phosphate carrier protein, mitochondrial

1

1

High-throughput

0.407

High

304196

RHOL
Ras-like GTP-binding protein RhoL

1

2

High-throughput

0.407

High

304201

Q59DP9
Calcium-transporting ATPase

1

5

High-throughput

0.407

High

304202

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

304211

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.407

High

304214

Q7KMQ0
26S proteasome regulatory subunit 7

1

3

High-throughput

0.407

High

304221

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.407

High

304225

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

304229

Q960C7
NADP-retinol dehydrogenase

1

3

High-throughput

0.407

High

304233

Q9V3V6
26S proteasome regulatory complex subunit p50

1

3

High-throughput

0.407

High

304234

Q9V3Z4
GH11341p

1

2

High-throughput

0.407

High

304235

Q9V405
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.407

High

304248

Q9VBZ8
ER membrane protein complex subunit 6

1

1

High-throughput

0.407

High

304252

IPO9
Importin-9

1

1

High-throughput

0.407

High

304260

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.407

High

304266

Q9VN44
FI07923p

1

2

High-throughput

0.407

High

304274

Q9VS57
RE14391p

1

1

High-throughput

0.407

High

304278

FRL
Formin-like protein

1

1

High-throughput

0.407

High

304280

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

3

High-throughput

0.407

High

304292

Q9W1B5
Glycerol-3-phosphate acyltransferase 4, isoform C

1

4

High-throughput

0.407

High

304296

Q9W414
Regulatory particle triple-A ATPase 4

1

3

High-throughput

0.407

High

304179

COX2
Cytochrome c oxidase subunit 2

2

0

High-throughput

0.298

High

304203

Q6NP72
GEO09659p1

2

0

High-throughput

0.298

High

304208

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

304215

Q7KN94
Electron transfer flavoprotein subunit alpha

2

0

High-throughput

0.298

High

304219

Q8IPV3
Uncharacterized protein, isoform A

2

0

High-throughput

0.298

High

304224

Q8SY53
GH11935p

2

0

High-throughput

0.298

High

304228

LDH
L-lactate dehydrogenase

2

0

High-throughput

0.298

High

304241

Q9V9Q4
LD43819p

2

0

High-throughput

0.298

High

304275

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

0

High-throughput

0.298

High

304281

Q9VV75
AT02348p

2

0

High-throughput

0.298

High

304298

QCR9
Cytochrome b-c1 complex subunit 9

2

0

High-throughput

0.298

High

195217

O16158
Calcium-binding protein

1

0

High-throughput

0.265

Low

304268

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

2697

A0A0B4LFU9
Anastral spindle 2, isoform B

1

0

High-throughput

0.232

Low

144851

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.232

Low

304183

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.232

Low

304184

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

304185

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

0

High-throughput

0.232

Low

304187

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

304194

Q0E9E2
Pyruvate carboxylase

1

0

High-throughput

0.232

Low

304195

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

304197

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.232

Low

304199

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

0

High-throughput

0.232

Low

304200

Q4QQB9
LP21121p

1

0

High-throughput

0.232

Low

304206

Q7JWI7
Hermes, isoform A

1

0

High-throughput

0.232

Low

304209

ARC1
Activity-regulated cytoskeleton associated protein 1

1

0

High-throughput

0.232

Low

304216

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

0

High-throughput

0.232

Low

304226

Q8T8W3
AT21416p

1

0

High-throughput

0.232

Low

304236

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

304237

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

304239

Q9V455
Importin subunit alpha

1

0

High-throughput

0.232

Low

304240

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

304242

Q9VAH7
N-terminal kinase-like protein

1

0

High-throughput

0.232

Low

304245

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.232

Low

304249

Q9VCF8
LD23561p

1

0

High-throughput

0.232

Low

304251

ELP6
Elongator complex protein 6

1

0

High-throughput

0.232

Low

304253

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.232

Low

304257

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

304258

Q9VK06
Phospholipid-transporting ATPase

1

0

High-throughput

0.232

Low

304261

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.232

Low

304263

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

0

High-throughput

0.232

Low

304265

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

304267

Q9VPR1
GH02075p

1

0

High-throughput

0.232

Low

304269

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

304270

Q9VQL7
Fatty acid synthase

1

0

High-throughput

0.232

Low

304272

Q9VQX6
LP05054p

1

0

High-throughput

0.232

Low

304273

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low

304277

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

304282

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.232

Low

304283

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

304284

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

0

High-throughput

0.232

Low

304287

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.232

Low

304289

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.232

Low

304291

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.232

Low

304293

Q9W1H8
acetyl-CoA C-acyltransferase

1

0

High-throughput

0.232

Low

304299

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025