Protein: ACSL5
Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 5) (LACS 5)

Gene: ACSL5
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9ULC5

Gene Ontology (top 5):
GO:0001676 - long-chain fatty acid metabolic process
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1134185

NTCP
Hepatic sodium/bile acid cotransporter

2

2

High-throughput

0.606

High

1186070

SOAT
Sodium-dependent organic anion transporter

2

2

High-throughput

0.606

High

253177

MOT2
Monocarboxylate transporter 2

2

0

High-throughput

0.580

High

1291524

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1348658

S7A14
Solute carrier family 7 member 14

2

0

High-throughput

0.580

High

1447178

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.580

High

436755

KPCB
Protein kinase C beta type

2

1

High-throughput

0.571

High

905782

CAV2
Caveolin-2

2

2

High-throughput

0.571

High

1143109

KPCD1
Serine/threonine-protein kinase D1

2

3

High-throughput

0.571

High

142116

PEX12
Peroxisome assembly protein 12

2

1

High-throughput

0.553

High

1109094

AQP6
Aquaporin-6

2

2

High-throughput

0.553

High

622485

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

717363

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

1096515

PAK1
Serine/threonine-protein kinase PAK 1

2

0

High-throughput

0.547

High

913614

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

1327814

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.521

High

1356257

Q8WU57
Ethanolaminephosphotransferase 1

1

1

High-throughput

0.515

High

230466

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.486

High

1421096

EPT1
Ethanolaminephosphotransferase 1

1

1

High-throughput

0.481

High

1461496

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

275130

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

2

High-throughput

0.479

High

401688

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

901670

RAB7A
Ras-related protein Rab-7a

1

4

Small-scale

0.479

High

965323

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

1005236

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1177661

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

1

High-throughput

0.479

High

1459279

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

227703

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

1385347

F136A
Protein FAM136A

1

0

High-throughput

0.458

High

1209787

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

66389

T238L
Transmembrane protein 238-like

1

0

Small-scale

0.426

High

140026

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

1449817

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025