Protein: NTCP
Hepatic sodium/bile acid cotransporter (Cell growth-inhibiting gene 29 protein) (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (NTCP) (Solute carrier family 10 member 1) (SLC10A1)

Gene: NTCP, SLC10A1
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q14973

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005886 - plasma membrane
GO:0008508 - bile acid:sodium symporter activity
GO:0015125 - bile acid transmembrane transporter activity
GO:0015721 - bile acid and bile salt transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1134135

BT2A2
Butyrophilin subfamily 2 member A2

1

1

High-throughput

0.621

High

189570

STX7
Syntaxin-7

2

7

High-throughput

0.606

High

456943

CO8A
Complement component C8 alpha chain

2

1

High-throughput

0.606

High

549440

CD20
B-lymphocyte antigen CD20

2

1

High-throughput

0.606

High

1031373

IFM3
Interferon-induced transmembrane protein 3

2

3

High-throughput

0.606

High

1092758

MALL
MAL-like protein

2

3

High-throughput

0.606

High

1132538

FXYD3
FXYD domain-containing ion transport regulator 3

2

3

High-throughput

0.606

High

1134099

VAMP3
Vesicle-associated membrane protein 3

2

3

High-throughput

0.606

High

1134109

TSPO2
Translocator protein 2

2

1

High-throughput

0.606

High

1134114

MFSD6
Major facilitator superfamily domain-containing protein 6

2

1

High-throughput

0.606

High

1134119

LRP10
Low-density lipoprotein receptor-related protein 10

2

2

High-throughput

0.606

High

1134122

S41A1
Solute carrier family 41 member 1

2

1

High-throughput

0.606

High

1134126

ORML3
ORM1-like protein 3

2

3

High-throughput

0.606

High

1134133

GP151
G-protein coupled receptor 151

2

1

High-throughput

0.606

High

1134137

CTR3
Cationic amino acid transporter 3

2

2

High-throughput

0.606

High

1134153

NEUR1
Sialidase-1

2

1

High-throughput

0.606

High

1134156

YIPF4
Protein YIPF4

2

2

High-throughput

0.606

High

1134162

FXYD6
FXYD domain-containing ion transport regulator 6

2

3

High-throughput

0.606

High

1134164

S38A1
Sodium-coupled neutral amino acid symporter 1

2

3

High-throughput

0.606

High

1134171

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

1

High-throughput

0.606

High

1134179

NINJ2
Ninjurin-2

2

1

High-throughput

0.606

High

1134185

ACSL5
Long-chain-fatty-acid--CoA ligase 5

2

2

High-throughput

0.606

High

1134191

S12A7
Solute carrier family 12 member 7

2

4

High-throughput

0.606

High

1134192

SELK
Selenoprotein K

2

1

High-throughput

0.606

High

1134167

ANTR1
Anthrax toxin receptor 1

2

1

High-throughput

0.601

High

261174

NSMA
Sphingomyelin phosphodiesterase 2

2

0

High-throughput

0.580

High

390576

TFR1
Transferrin receptor protein 1

2

0

High-throughput

0.580

High

455911

ASGR1
Asialoglycoprotein receptor 1

2

0

High-throughput

0.580

High

1134117

OTOP3
Proton channel OTOP3

2

0

High-throughput

0.580

High

1134118

MOT13
Monocarboxylate transporter 13

2

0

High-throughput

0.580

High

1134129

CLD19
Claudin-19

2

0

High-throughput

0.580

High

1134132

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.580

High

1134141

LFG3
Protein lifeguard 3

2

0

High-throughput

0.580

High

1134152

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

0

High-throughput

0.580

High

1134160

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

1134178

GDE1
Glycerophosphodiester phosphodiesterase 1

2

0

High-throughput

0.580

High

1090022

NTCP2
Ileal sodium/bile acid cotransporter

1

1

High-throughput

0.575

High

49646

T120B
Transmembrane protein 120B

2

1

High-throughput

0.553

High

160268

GOSR2
Golgi SNAP receptor complex member 2

2

1

High-throughput

0.553

High

335551

BMP10
Bone morphogenetic protein 10

2

1

High-throughput

0.553

High

339217

SFT2B
Vesicle transport protein SFT2B

2

2

High-throughput

0.553

High

359987

NB5R3
NADH-cytochrome b5 reductase 3

2

1

High-throughput

0.553

High

636216

MAL
Myelin and lymphocyte protein

2

3

High-throughput

0.553

High

873393

LSS
Lanosterol synthase

2

1

High-throughput

0.553

High

1043124

TAP1
Antigen peptide transporter 1

2

1

High-throughput

0.553

High

1134102

ORML2
ORM1-like protein 2

2

3

High-throughput

0.553

High

1134103

UNC50
Protein unc-50 homolog

2

1

High-throughput

0.553

High

1134108

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

2

1

High-throughput

0.553

High

1134111

S35E4
Solute carrier family 35 member E4

2

1

High-throughput

0.553

High

1134113

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

1

High-throughput

0.553

High

1134116

FA2H
Fatty acid 2-hydroxylase

2

3

High-throughput

0.553

High

1134127

S66A2
Solute carrier family 66 member 2

2

1

High-throughput

0.553

High

1134134

SFT2A
Vesicle transport protein SFT2A

2

2

High-throughput

0.553

High

1134136

TM239
Transmembrane protein 239

2

1

High-throughput

0.553

High

1134138

TM234
Transmembrane protein 234

2

1

High-throughput

0.553

High

1134140

SCAM4
Secretory carrier-associated membrane protein 4

2

2

High-throughput

0.553

High

1134142

S2546
Mitochondrial outer membrane protein SLC25A46

2

1

High-throughput

0.553

High

1134145

YIPF6
Protein YIPF6

2

2

High-throughput

0.553

High

1134146

GIMA5
GTPase IMAP family member 5

2

2

High-throughput

0.553

High

1134148

RUSF1
RUS family member 1

2

1

High-throughput

0.553

High

1134149

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

1

High-throughput

0.553

High

1134151

CKLF3
CKLF-like MARVEL transmembrane domain-containing protein 3

2

4

High-throughput

0.553

High

1134158

DERL1
Derlin-1

2

1

High-throughput

0.553

High

1134161

FHR5
Complement factor H-related protein 5

2

1

High-throughput

0.553

High

1134163

TM222
Transmembrane protein 222

2

2

High-throughput

0.553

High

1134165

TMM60
Transmembrane protein 60

2

1

High-throughput

0.553

High

1134168

SFXN1
Sideroflexin-1

2

1

High-throughput

0.553

High

1134172

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

1

High-throughput

0.553

High

1134174

S38A7
Sodium-coupled neutral amino acid transporter 7

2

3

High-throughput

0.553

High

1134175

TM242
Transmembrane protein 242

2

1

High-throughput

0.553

High

1134177

TV23B
Golgi apparatus membrane protein TVP23 homolog B

2

1

High-throughput

0.553

High

1134181

ORML1
ORM1-like protein 1

2

3

High-throughput

0.553

High

1134189

PEX16
Peroxisomal membrane protein PEX16

2

1

High-throughput

0.553

High

563776

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

1134169

AT131
Endoplasmic reticulum transmembrane helix translocase

2

2

High-throughput

0.526

High

1134124

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.513

High

162196

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.481

High

333006

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.481

High

1030358

PMP22
Peripheral myelin protein 22

1

1

High-throughput

0.481

High

1031632

IFM2
Interferon-induced transmembrane protein 2

1

3

High-throughput

0.481

High

1127884

S29A2
Equilibrative nucleoside transporter 2

1

3

High-throughput

0.481

High

1134101

TM119
Transmembrane protein 119

1

1

High-throughput

0.481

High

1134106

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.481

High

1134107

RTP2
Receptor-transporting protein 2

1

1

High-throughput

0.481

High

1134123

TARG1
Trafficking regulator of GLUT4 1

1

3

High-throughput

0.481

High

1134183

PRAF1
Prenylated Rab acceptor protein 1

1

1

High-throughput

0.481

High

1134184

LCAP
Leucyl-cystinyl aminopeptidase

1

1

High-throughput

0.481

High

63653

A5PKU2
TUSC5 protein

1

3

High-throughput

0.470

High

116729

I3L0A0
HCG2044781

1

3

High-throughput

0.470

High

1134110

Q6IBB0
IFITM2 protein

1

3

High-throughput

0.470

High

1134147

Q96FB2
SLC29A2 protein

1

3

High-throughput

0.470

High

718694

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

1134100

NKG7
Protein NKG7

1

0

High-throughput

0.460

High

1134105

SGMR2
Sigma intracellular receptor 2

1

0

High-throughput

0.460

High

299197

FLOT1
Flotillin-1

1

2

High-throughput

0.445

High

420795

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.445

High

522664

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.445

High

631649

RAB6A
Ras-related protein Rab-6A

1

5

High-throughput

0.445

High

658885

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

4

High-throughput

0.445

High

900818

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.445

High

931361

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

1

High-throughput

0.445

High

1124806

FLOT2
Flotillin-2

1

2

High-throughput

0.445

High

1134098

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.445

High

1134139

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.445

High

1134182

S12A6
Solute carrier family 12 member 6

1

4

High-throughput

0.445

High

1134187

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.445

High

63823

PEDS1
Plasmanylethanolamine desaturase 1

1

3

High-throughput

0.439

High

209014

CYB5B
Cytochrome b5 type B

1

3

High-throughput

0.439

High

295683

UPK1B
Uroplakin-1b

1

2

High-throughput

0.439

High

391735

STAT
Statherin

1

1

High-throughput

0.439

High

1125435

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.439

High

1134121

STX12
Syntaxin-12

1

7

High-throughput

0.439

High

1134150

SC22A
Vesicle-trafficking protein SEC22a

1

1

High-throughput

0.439

High

1134159

EMC6
ER membrane protein complex subunit 6

1

2

High-throughput

0.439

High

1134190

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

1

High-throughput

0.439

High

1134193

SERP1
Stress-associated endoplasmic reticulum protein 1

1

2

High-throughput

0.439

High

609679

LEG3
Galectin-3

1

0

High-throughput

0.426

High

690253

STOM
Stomatin

1

0

High-throughput

0.426

High

1134131

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.426

High

1134170

WDR6
tRNA

1

0

High-throughput

0.426

High

1134173

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.426

High

322727

RHBT3
Rho-related BTB domain-containing protein 3

1

1

High-throughput

0.407

High

976276

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.407

High

1134104

RAB6D
Ras-related protein Rab-6D

1

5

High-throughput

0.407

High

1134180

MTCH1
Mitochondrial carrier homolog 1

1

2

High-throughput

0.407

High

1134130

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

3

0

High-throughput

0.337

High

64737

MADL2
Myeloid-associated differentiation marker-like protein 2

2

0

High-throughput

0.316

High

325547

YIF1A
Protein YIF1A

2

0

High-throughput

0.316

High

350366

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

377857

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.316

High

444680

CO2
Complement C2

2

0

High-throughput

0.316

High

789895

FDFT
Squalene synthase

2

0

High-throughput

0.316

High

1059071

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.316

High

1134115

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

2

0

High-throughput

0.316

High

1134143

TOM6
Mitochondrial import receptor subunit TOM6 homolog

2

0

High-throughput

0.316

High

1134144

F241B
Protein FAM241B

2

0

High-throughput

0.316

High

1134154

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

2

0

High-throughput

0.316

High

1134157

TM121
Transmembrane protein 121

2

0

High-throughput

0.316

High

1134120

IFTAP
Intraflagellar transport-associated protein

1

0

High-throughput

0.282

High

1134125

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.279

Low

1134128

ZN276
Zinc finger protein 276

1

0

High-throughput

0.279

Low

1134176

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

331470

APOL3
Apolipoprotein L3

1

0

High-throughput

0.251

Low

894755

EMD
Emerin

1

0

High-throughput

0.251

Low

1134188

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.251

Low

716429

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.232

Low

1134112

TM214
Transmembrane protein 214

1

0

High-throughput

0.232

Low

1134155

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.232

Low

1134166

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.232

Low

1134186

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025