Protein: ALPK2
Alpha-protein kinase 2 (EC 2.7.11.1) (Heart alpha-protein kinase)

Gene: ALPK2
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q86TB3

Gene Ontology (top 5):
GO:0003007 - heart morphogenesis
GO:0003308 - negative regulation of Wnt signaling pathway involved in heart development
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0010468 - regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

909067

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.691

High

1287086

KC1G3
Casein kinase I isoform gamma-3

1

2

High-throughput

0.691

High

272290

OBSL1
Obscurin-like protein 1

1

17

High-throughput

0.618

High

993431

ACTH
Actin, gamma-enteric smooth muscle

1

8

High-throughput

0.618

High

1287079

CERK1
Ceramide kinase

1

0

High-throughput

0.513

High

287957

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

6

High-throughput

0.489

High

333073

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

7

High-throughput

0.489

High

504744

FBSP1
F-box/SPRY domain-containing protein 1

1

17

High-throughput

0.489

High

732636

ARRB2
Beta-arrestin-2

1

2

High-throughput

0.489

High

882521

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.489

High

1151566

TRIP6
Thyroid receptor-interacting protein 6

1

9

High-throughput

0.489

High

1236174

NAA16
N-alpha-acetyltransferase 16, NatA auxiliary subunit

1

4

High-throughput

0.489

High

1287078

SPRY3
SPRY domain-containing protein 3

1

10

High-throughput

0.489

High

1287081

TRI41
E3 ubiquitin-protein ligase TRIM41

1

3

High-throughput

0.489

High

1287082

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

3

High-throughput

0.489

High

1287084

HYPK
Huntingtin-interacting protein K

1

1

High-throughput

0.489

High

1287085

VAPA
Vesicle-associated membrane protein-associated protein A

1

7

High-throughput

0.489

High

521782

H14
Histone H1.4

1

5

High-throughput

0.470

High

551130

PCNA
Proliferating cell nuclear antigen

1

5

High-throughput

0.437

High

1287080

KCNV2
Potassium voltage-gated channel subfamily V member 2

1

3

High-throughput

0.437

High

944396

SYJ2B
Synaptojanin-2-binding protein

1

10

High-throughput

0.407

High

66796

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

833649

NAA10
N-alpha-acetyltransferase 10

1

0

High-throughput

0.279

Low

1234694

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.279

Low

1287083

STN1
CST complex subunit STN1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025