Protein: RNF10
E3 ubiquitin-protein ligase RNF10 (EC 2.3.2.27) (RING finger protein 10)

Gene: RNF10
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q8N5U6

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006513 - protein monoubiquitination
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

982244

UB2D2
Ubiquitin-conjugating enzyme E2 D2

5

20

High-throughput

0.931

High

1328511

UB2E3
Ubiquitin-conjugating enzyme E2 E3

3

20

High-throughput

0.875

High

906704

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

High-throughput

0.817

High

957132

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

High-throughput

0.817

High

1089232

TRI26
Tripartite motif-containing protein 26

2

1

High-throughput

0.817

High

1328538

UB2D4
Ubiquitin-conjugating enzyme E2 D4

2

20

High-throughput

0.817

High

909347

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

970780

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

993654

UBC9
SUMO-conjugating enzyme UBC9

1

20

High-throughput

0.698

High

1103915

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

1328512

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1328515

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

High-throughput

0.698

High

1328522

TRI55
Tripartite motif-containing protein 55

1

9

High-throughput

0.698

High

1328524

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

High-throughput

0.698

High

242279

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.665

High

1218731

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

1324407

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

20

High-throughput

0.621

High

1328510

TRI63
E3 ubiquitin-protein ligase TRIM63

1

7

High-throughput

0.621

High

1096100

TADBP
TAR DNA-binding protein 43

2

7

High-throughput

0.601

High

954194

RS20
Small ribosomal subunit protein uS10

2

1

Small-scale

0.595

High

791534

SYUA
Alpha-synuclein

2

0

Small-scale

0.585

High

860839

RS10
Small ribosomal subunit protein eS10

2

1

Small-scale

0.585

High

1328519

HAUS8
HAUS augmin-like complex subunit 8

2

0

High-throughput

0.576

High

1328516

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

3

High-throughput

0.575

High

894017

MEOX2
Homeobox protein MOX-2

1

2

Small-scale

0.573

High

928492

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.573

High

1328507

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

0

High-throughput

0.560

High

1328530

UBTD1
Ubiquitin domain-containing protein 1

1

1

Small-scale

0.555

High

279421

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

1047844

TLE1
Transducin-like enhancer protein 1

1

5

High-throughput

0.541

High

1139762

SETB1
Histone-lysine N-methyltransferase SETDB1

1

2

High-throughput

0.541

High

193128

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

3

High-throughput

0.536

High

274898

LRP5
Low-density lipoprotein receptor-related protein 5

1

1

High-throughput

0.536

High

341989

CEP43
Centrosomal protein 43

1

1

High-throughput

0.536

High

537517

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.536

High

1328504

ARI1B
AT-rich interactive domain-containing protein 1B

1

4

High-throughput

0.536

High

1328514

DCAF5
DDB1- and CUL4-associated factor 5

1

6

High-throughput

0.536

High

1328520

DDX23
Probable ATP-dependent RNA helicase DDX23

1

5

High-throughput

0.536

High

1328537

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

1

High-throughput

0.536

High

996243

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

1028283

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.518

High

1123518

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

1328509

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

130987

HIP1
Huntingtin-interacting protein 1

1

3

High-throughput

0.515

High

246042

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.515

High

415720

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

937062

CASP6
Caspase-6

1

2

High-throughput

0.515

High

981586

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.515

High

1328540

RNF11
RING finger protein 11

1

4

High-throughput

0.515

High

1117245

NCOA4
Nuclear receptor coactivator 4

1

0

High-throughput

0.513

High

1328533

TBCC1
TBCC domain-containing protein 1

1

0

High-throughput

0.513

High

1328541

P2R3B
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta

1

0

High-throughput

0.513

High

324013

CSTN1
Calsyntenin-1

1

0

High-throughput

0.511

High

246760

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.508

High

987775

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.508

High

658274

RS3
Small ribosomal subunit protein uS3

1

4

Small-scale

0.501

High

297360

DYSF
Dysferlin

1

1

High-throughput

0.494

High

1328521

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.494

High

261636

CATL2
Cathepsin L2

1

3

High-throughput

0.489

High

1217480

CE350
Centrosome-associated protein 350

1

4

High-throughput

0.489

High

1328531

PDLI7
PDZ and LIM domain protein 7

1

4

High-throughput

0.489

High

173070

XPO1
Exportin-1

1

8

High-throughput

0.479

High

461707

HS90A
Heat shock protein HSP 90-alpha

1

11

High-throughput

0.479

High

468597

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

551155

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

595514

H15
Histone H1.5

1

1

High-throughput

0.479

High

730770

1433S
14-3-3 protein sigma

1

7

High-throughput

0.479

High

971781

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.479

High

982735

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

1049557

1433F
14-3-3 protein eta

1

7

High-throughput

0.479

High

1328502

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1328528

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1328535

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

109462

G5E9A7
DM1 locus, WD repeat containing

1

5

High-throughput

0.470

High

280722

PR40A
Pre-mRNA-processing factor 40 homolog A

1

3

High-throughput

0.470

High

1328505

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.470

High

959000

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

1215712

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

1056846

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.457

High

1217158

RIF1
Telomere-associated protein RIF1

1

4

High-throughput

0.457

High

809726

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.445

High

1098058

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.445

High

1117599

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.445

High

1146513

TTF1
Transcription termination factor 1

1

2

High-throughput

0.445

High

1150668

TRBP2
RISC-loading complex subunit TARBP2

1

4

High-throughput

0.445

High

1245804

ATAD2
ATPase family AAA domain-containing protein 2

1

7

High-throughput

0.445

High

1316838

ASPM
Abnormal spindle-like microcephaly-associated protein

1

4

High-throughput

0.445

High

1328334

ZC3H8
Zinc finger CCCH domain-containing protein 8

1

2

High-throughput

0.445

High

1328503

LS14A
Protein LSM14 homolog A

1

3

High-throughput

0.445

High

1328523

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.445

High

1328536

BAZ1B
Tyrosine-protein kinase BAZ1B

1

5

High-throughput

0.445

High

1328532

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1306877

INLR1
Interferon lambda receptor 1

1

1

Small-scale

0.437

High

1327081

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

67029

ZN729
Zinc finger protein 729

1

0

High-throughput

0.426

High

1112087

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.426

High

1148206

DLGP5
Disks large-associated protein 5

1

0

High-throughput

0.426

High

1187978

GON4L
GON-4-like protein

1

0

High-throughput

0.426

High

1328508

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.426

High

1328539

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.426

High

712112

CO4A5

1

1

High-throughput

0.417

High

182328

WDR46
WD repeat-containing protein 46

1

2

High-throughput

0.407

High

1008076

DEN2B
DENN domain-containing protein 2B

1

1

High-throughput

0.407

High

1203874

NOM1
Nucleolar MIF4G domain-containing protein 1

1

5

High-throughput

0.407

High

1206943

CEP78
Centrosomal protein of 78 kDa

1

1

High-throughput

0.407

High

1328527

YTDC2
3'-5' RNA helicase YTHDC2

1

3

High-throughput

0.407

High

322431

HAUS5
HAUS augmin-like complex subunit 5

2

0

High-throughput

0.313

High

1278411

HAUS6
HAUS augmin-like complex subunit 6

2

0

High-throughput

0.313

High

1328525

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

505179

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

813156

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

1228551

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.279

Low

1328506

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.279

Low

1328513

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.279

Low

1328517

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.279

Low

1328518

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

1328526

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.279

Low

1328534

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.279

Low

301561

WFS1
Wolframin

1

0

High-throughput

0.268

Low

562228

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

1279634

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1212419

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

106269

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

947019

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

134335

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.232

Low

1150299

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.232

Low

1208780

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.232

Low

1328529

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025