Protein: ZBTB1
Zinc finger and BTB domain-containing protein 1

Gene: ZBTB1
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q9Y2K1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production
GO:0002682 - regulation of immune system process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

622131

ZBT25
Zinc finger and BTB domain-containing protein 25

3

20

High-throughput

0.861

High

66719

ZN785
Zinc finger protein 785

2

20

High-throughput

0.811

High

735119

ZNF76
Zinc finger protein 76

2

19

High-throughput

0.811

High

507592

PIM1
Serine/threonine-protein kinase pim-1

1

2

High-throughput

0.740

High

1189203

ZN572
Zinc finger protein 572

1

18

High-throughput

0.740

High

1251806

ZN417
Zinc finger protein 417

1

18

High-throughput

0.740

High

1056002

ZN460
Zinc finger protein 460

1

20

High-throughput

0.691

High

1235471

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

2

High-throughput

0.625

High

861993

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.618

High

1042878

CUL3
Cullin-3

1

20

High-throughput

0.618

High

1069671

STK38
Serine/threonine-protein kinase 38

1

1

Small-scale

0.618

High

1235713

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

18

Small-scale

0.618

High

1107964

F161A
Protein FAM161A

3

1

High-throughput

0.616

High

1304968

NECD
Necdin

2

5

High-throughput

0.613

High

875770

MFAP1
Microfibrillar-associated protein 1

2

2

High-throughput

0.606

High

1273543

KAT5
Histone acetyltransferase KAT5

2

1

High-throughput

0.606

High

1314699

SCNM1
Sodium channel modifier 1

2

1

High-throughput

0.606

High

1157634

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.602

High

1335765

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.602

High

1244906

GP156
Probable G-protein coupled receptor 156

2

1

High-throughput

0.574

High

967523

EWS
RNA-binding protein EWS

1

6

High-throughput

0.541

High

1295366

MAML3
Mastermind-like protein 3

1

2

High-throughput

0.541

High

174447

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.536

High

1263198

PALLD
Palladin

1

1

High-throughput

0.536

High

1219928

TRI42
Tripartite motif-containing protein 42

1

20

High-throughput

0.523

High

1332797

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1023840

TRAF1
TNF receptor-associated factor 1

1

8

High-throughput

0.512

High

476598

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.501

High

517550

PCNA
Proliferating cell nuclear antigen

1

2

Small-scale

0.501

High

930464

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

615500

KALM
Anosmin-1

1

10

High-throughput

0.489

High

680396

SDC4
Syndecan-4

1

2

High-throughput

0.489

High

1052187

MAP7
Ensconsin

1

6

High-throughput

0.489

High

487860

ANDR
Androgen receptor

1

19

Small-scale

0.481

High

163494

XPO1
Exportin-1

1

4

High-throughput

0.479

High

232605

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

296183

MTA2
Metastasis-associated protein MTA2

1

2

Small-scale

0.479

High

321856

WIZ
Protein Wiz

1

20

Small-scale

0.479

High

370755

ESR1
Estrogen receptor

1

19

Small-scale

0.479

High

376345

ANXA1
Annexin A1

1

2

Small-scale

0.479

High

388812

HSPB1
Heat shock protein beta-1

1

2

Small-scale

0.479

High

401189

RLA0
Large ribosomal subunit protein uL10

1

4

Small-scale

0.479

High

428510

TBB5
Tubulin beta chain

1

1

Small-scale

0.479

High

445590

RSSA
Small ribosomal subunit protein uS2

1

5

Small-scale

0.479

High

453938

RU2A
U2 small nuclear ribonucleoprotein A'

1

2

Small-scale

0.479

High

470211

H2AZ
Histone H2A.Z

1

3

Small-scale

0.479

High

504988

HSP7C
Heat shock cognate 71 kDa protein

1

4

Small-scale

0.479

High

551873

DESP
Desmoplakin

1

4

Small-scale

0.479

High

559299

H15
Histone H1.5

1

15

Small-scale

0.479

High

582571

NUCL
Nucleolin

1

1

Small-scale

0.479

High

598386

FLNA
Filamin-A

1

2

Small-scale

0.479

High

714100

HS71L
Heat shock 70 kDa protein 1-like

1

4

Small-scale

0.479

High

727944

SOX6
Transcription factor SOX-6

1

7

High-throughput

0.479

High

749979

BRCA1
Breast cancer type 1 susceptibility protein

1

16

High-throughput

0.479

High

760397

RL3
Large ribosomal subunit protein uL3

1

7

Small-scale

0.479

High

773638

RL13A
Large ribosomal subunit protein uL13

1

5

Small-scale

0.479

High

805853

RL27A
Large ribosomal subunit protein uL15

1

2

Small-scale

0.479

High

807058

RS9
Small ribosomal subunit protein uS4

1

3

Small-scale

0.479

High

892130

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.479

High

907601

RS8
Small ribosomal subunit protein eS8

1

2

Small-scale

0.479

High

908225

RS16
Small ribosomal subunit protein uS9

1

7

Small-scale

0.479

High

910621

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

911302

RS13
Small ribosomal subunit protein uS15

1

1

Small-scale

0.479

High

922026

RL30
Large ribosomal subunit protein eL30

1

3

Small-scale

0.479

High

923287

RL11
Large ribosomal subunit protein uL5

1

3

Small-scale

0.479

High

928044

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

1

Small-scale

0.479

High

934033

TBB4B
Tubulin beta-4B chain

1

1

Small-scale

0.479

High

958156

RBM10
RNA-binding protein 10

1

1

Small-scale

0.479

High

963033

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

High-throughput

0.479

High

990006

RL18
Large ribosomal subunit protein eL18

1

1

Small-scale

0.479

High

992998

SRSF1
Serine/arginine-rich splicing factor 1

1

14

Small-scale

0.479

High

1030042

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.479

High

1038838

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

1057031

MDC1
Mediator of DNA damage checkpoint protein 1

1

4

High-throughput

0.479

High

1066907

KIF14
Kinesin-like protein KIF14

1

7

Small-scale

0.479

High

1074270

SF3A1
Splicing factor 3A subunit 1

1

2

Small-scale

0.479

High

1084455

SRSF7
Serine/arginine-rich splicing factor 7

1

8

Small-scale

0.479

High

1230576

CCAR2
Cell cycle and apoptosis regulator protein 2

1

3

Small-scale

0.479

High

1236586

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

High-throughput

0.479

High

1266157

DDX1
ATP-dependent RNA helicase DDX1

1

1

Small-scale

0.479

High

1285403

PF21A
PHD finger protein 21A

1

15

High-throughput

0.479

High

1309320

MEP50
Methylosome protein WDR77

1

2

Small-scale

0.479

High

1315913

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1354413

ZMYM2
Zinc finger MYM-type protein 2

1

2

High-throughput

0.479

High

1354916

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1356500

RCOR1
REST corepressor 1

1

2

High-throughput

0.479

High

1357686

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

Small-scale

0.479

High

1377289

MTCL1
Microtubule cross-linking factor 1

1

2

Small-scale

0.479

High

1315455

HEMGN
Hemogen

1

0

Small-scale

0.460

High

202329

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

0

Small-scale

0.458

High

518539

ADT3
ADP/ATP translocase 3

1

0

Small-scale

0.458

High

780352

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

788948

RS27
Small ribosomal subunit protein eS27

1

0

Small-scale

0.458

High

852209

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

0

Small-scale

0.458

High

899887

RL27
Large ribosomal subunit protein eL27

1

0

Small-scale

0.458

High

902815

SUMO2
Small ubiquitin-related modifier 2

1

0

Small-scale

0.458

High

907786

RS15A
Small ribosomal subunit protein uS8

1

0

Small-scale

0.458

High

910780

RS23
Small ribosomal subunit protein uS12

1

0

Small-scale

0.458

High

911068

RS29
Small ribosomal subunit protein uS14

1

0

Small-scale

0.458

High

911561

RS11
Small ribosomal subunit protein uS17

1

0

Small-scale

0.458

High

912758

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

Small-scale

0.458

High

915125

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

Small-scale

0.458

High

920588

RS25
Small ribosomal subunit protein eS25

1

0

Small-scale

0.458

High

923599

RL8
Large ribosomal subunit protein uL2

1

0

Small-scale

0.458

High

995938

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

Small-scale

0.458

High

1027832

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.458

High

1046272

BLMH
Bleomycin hydrolase

1

0

Small-scale

0.458

High

1047475

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

1263999

P66B
Transcriptional repressor p66-beta

1

0

Small-scale

0.458

High

1301727

TESK2
Dual specificity testis-specific protein kinase 2

1

0

Small-scale

0.458

High

1348480

BCLF1
Bcl-2-associated transcription factor 1

1

0

Small-scale

0.458

High

618741

IF4B
Eukaryotic translation initiation factor 4B

1

1

Small-scale

0.437

High

842729

RL14
Large ribosomal subunit protein eL14

1

4

Small-scale

0.437

High

933395

TBA1B
Tubulin alpha-1B chain

1

2

Small-scale

0.437

High

959343

S25A3
Solute carrier family 25 member 3

1

1

Small-scale

0.437

High

994031

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

3

Small-scale

0.437

High

1045569

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

Small-scale

0.437

High

1301339

PEO1
Twinkle mtDNA helicase

1

1

Small-scale

0.437

High

1354023

CRNN
Cornulin

1

7

Small-scale

0.437

High

1377290

O51B4
Olfactory receptor 51B4

1

1

Small-scale

0.437

High

1295621

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

1132810

TRML2
Trem-like transcript 2 protein

3

0

High-throughput

0.347

High

204523

ARK72
Aflatoxin B1 aldehyde reductase member 2

3

0

High-throughput

0.339

High

371477

KLKB1
Plasma kallikrein

2

0

High-throughput

0.328

High

1109010

ASTRB
Protein Aster-B

2

0

High-throughput

0.328

High

1233631

SPA6L
Spermatogenesis associated 6-like protein

2

0

High-throughput

0.318

High

1262342

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

608909

SPR2E
Small proline-rich protein 2E

1

0

Small-scale

0.249

Low

778338

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

Small-scale

0.249

Low

825278

RL34
Large ribosomal subunit protein eL34

1

0

Small-scale

0.249

Low

854862

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

Small-scale

0.249

Low

949591

RL24
Large ribosomal subunit protein eL24

1

0

Small-scale

0.249

Low

1288544

MUCL1
Mucin-like protein 1

1

0

Small-scale

0.249

Low

1297692

CCD42
Coiled-coil domain-containing protein 42

1

0

Small-scale

0.249

Low

1308988

TRIR
Telomerase RNA component interacting RNase

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024