Protein: SAMP
Serum amyloid P-component (SAP) (9.5S alpha-1-glycoprotein) [Cleaved into: Serum amyloid P-component(1-203)]

Gene: SAMP, APCS
Organism: Homo sapiens
Interactions: 32
UniProt ID: P02743

Gene Ontology (top 5):
GO:0001849 - complement component C1q complex binding
GO:0002674 - negative regulation of acute inflammatory response
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

388569

SAMP
Serum amyloid P-component

4

8

Small-scale

0.900

High

268908

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

6

Small-scale

0.647

High

388477

CRP

1

8

Small-scale

0.647

High

388574

FCG3A
Low affinity immunoglobulin gamma Fc region receptor III-A

1

6

Small-scale

0.647

High

388576

FCGR1
High affinity immunoglobulin gamma Fc receptor I

1

6

Small-scale

0.647

High

388572

A4
Amyloid-beta precursor protein

2

2

Small-scale

0.611

High

388582

ALX1
ALX homeobox protein 1

2

1

High-throughput

0.606

High

388571

C4BPA
C4b-binding protein alpha chain

2

6

Small-scale

0.571

High

388593

CERT
Ceramide transfer protein

1

1

Small-scale

0.538

High

132975

MATN2
Matrilin-2

1

1

High-throughput

0.536

High

388589

TX101
Testis-expressed protein 101

1

2

High-throughput

0.536

High

388585

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.518

High

388588

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

388591

PHF11
PHD finger protein 11

1

0

High-throughput

0.513

High

388579

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

388587

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

361987

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.486

High

388580

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.486

High

388581

HES1
Transcription factor HES-1

1

0

High-throughput

0.486

High

229611

CALU
Calumenin

1

0

Small-scale

0.480

High

277239

PITX3
Pituitary homeobox 3

1

1

Small-scale

0.479

High

388570

FINC
Fibronectin

1

3

Small-scale

0.479

High

388575

MBL2
Mannose-binding protein C

1

3

Small-scale

0.479

High

388577

FCAR
Immunoglobulin alpha Fc receptor

1

3

Small-scale

0.479

High

388578

GLPK
Glycerol kinase

1

0

High-throughput

0.460

High

388573

CATB
Cathepsin B

1

0

Small-scale

0.458

High

388590

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.458

High

388583

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

0

High-throughput

0.279

Low

388584

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

388586

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

388592

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025