Protein: PROC
Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]

Gene: PROC
Organism: Homo sapiens
Interactions: 16
UniProt ID: P04070

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

402466

IPSP
Plasma serine protease inhibitor

2

20

Small-scale

0.755

High

402468

PROS
Vitamin K-dependent protein S

1

18

High-throughput

0.691

High

402467

KLK1
Kallikrein-1

1

17

Small-scale

0.647

High

402470

WNT5A
Protein Wnt-5a

2

3

High-throughput

0.628

High

402475

NPB
Neuropeptide B

2

0

High-throughput

0.602

High

402477

EPHA6
Ephrin type-A receptor 6

2

16

High-throughput

0.574

High

390352

PLF4
Platelet factor 4

1

1

Small-scale

0.501

High

402473

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

402478

EPCR
Endothelial protein C receptor

1

0

Small-scale

0.480

High

402472

MMP15
Matrix metalloproteinase-15

1

0

Small-scale

0.458

High

402474

H33
Histone H3.3

1

0

High-throughput

0.458

High

402476

DEFM
Peptide deformylase, mitochondrial

2

0

High-throughput

0.328

High

70078

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

402469

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

402471

MATR3
Matrin-3

1

0

High-throughput

0.269

Low

402465

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025