Protein: MMP15
Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2)

Gene: MMP15
Organism: Homo sapiens
Interactions: 37
UniProt ID: P51511

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008047 - enzyme activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902993

MOG
Myelin-oligodendrocyte glycoprotein

1

1

High-throughput

0.691

High

168392

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.656

High

903003

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.656

High

139196

UPK2
Uroplakin-2

2

0

High-throughput

0.576

High

590839

TIMP2
Metalloproteinase inhibitor 2

1

20

Small-scale

0.575

High

894402

MMP14
Matrix metalloproteinase-14

1

5

High-throughput

0.575

High

328882

RTN3
Reticulon-3

1

1

High-throughput

0.536

High

518819

CCL3
C-C motif chemokine 3

1

5

High-throughput

0.536

High

902990

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.536

High

902991

IL5RA
Interleukin-5 receptor subunit alpha

1

2

High-throughput

0.536

High

903002

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

903007

DKKL1
Dickkopf-like protein 1

1

2

High-throughput

0.536

High

903010

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.536

High

224472

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.513

High

547988

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

903000

TRPV3
Transient receptor potential cation channel subfamily V member 3

1

0

High-throughput

0.513

High

903001

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

903009

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

465953

CO1A2
Collagen alpha-2(I) chain

1

20

Small-scale

0.501

High

567819

PRG2
Bone marrow proteoglycan

1

11

High-throughput

0.489

High

903004

GORS2
Golgi reassembly-stacking protein 2

1

1

High-throughput

0.489

High

157112

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

241132

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

402472

PROC
Vitamin K-dependent protein C

1

0

Small-scale

0.458

High

254892

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

538741

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.426

High

902997

SV2B
Synaptic vesicle glycoprotein 2B

1

0

High-throughput

0.426

High

902998

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.426

High

903005

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.426

High

903006

LAT2
Large neutral amino acids transporter small subunit 2

1

0

High-throughput

0.426

High

902996

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

903008

TMED7
Transmembrane emp24 domain-containing protein 7

1

0

High-throughput

0.279

Low

425385

ISG15
Ubiquitin-like protein ISG15

1

0

Small-scale

0.249

Low

902992

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

902994

MKS3
Meckelin

1

0

High-throughput

0.249

Low

902995

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

902999

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025