Protein: DEFM
Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase)

Gene: DEFM, PDF
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9HBH1

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0006412 - translation
GO:0008284 - positive regulation of cell population proliferation
GO:0018206 - peptidyl-methionine modification
GO:0042586 - peptide deformylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

246143

KIF1B
Kinesin-like protein KIF1B

2

0

High-throughput

0.602

High

1012621

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.602

High

1249439

OLFM4
Olfactomedin-4

2

0

High-throughput

0.585

High

1438289

RBX2
RING-box protein 2

2

0

High-throughput

0.576

High

1438290

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

1

High-throughput

0.536

High

298273

BODG
Gamma-butyrobetaine dioxygenase

1

0

High-throughput

0.513

High

341362

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

349708

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.513

High

378441

IFNG
Interferon gamma

1

0

High-throughput

0.513

High

593502

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

869245

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1119436

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

0

High-throughput

0.513

High

1218913

IL23R
Interleukin-23 receptor

1

0

High-throughput

0.513

High

1258315

MOB2
MOB kinase activator 2

1

0

High-throughput

0.513

High

1310425

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1380912

RAB24
Ras-related protein Rab-24

1

0

High-throughput

0.513

High

1405615

TSNAX
Translin-associated protein X

1

0

High-throughput

0.513

High

1438287

GKN1
Gastrokine-1

1

0

High-throughput

0.513

High

856929

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.489

High

1419451

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

1

High-throughput

0.489

High

1367320

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1438292

TFR2
Transferrin receptor protein 2

1

1

High-throughput

0.437

High

1438285

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.426

High

95947

E7ET36
Transferrin receptor 2

1

1

High-throughput

0.407

High

1116305

PTC1
Protein patched homolog 1

3

0

High-throughput

0.347

High

1295038

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

369752

A2MG
Alpha-2-macroglobulin

2

0

High-throughput

0.328

High

388558

CRP

2

0

High-throughput

0.328

High

402476

PROC
Vitamin K-dependent protein C

2

0

High-throughput

0.328

High

1030814

DEF5
Defensin alpha 5

2

0

High-throughput

0.328

High

1086187

CETN1
Centrin-1

2

0

High-throughput

0.328

High

1278573

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

641678

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

0

High-throughput

0.318

High

1316545

MCLN2
Mucolipin-2

2

0

High-throughput

0.313

High

177406

ARHGB
Rho guanine nucleotide exchange factor 11

2

0

High-throughput

0.298

High

133585

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

231343

EFNA2
Ephrin-A2

1

0

High-throughput

0.279

Low

377004

ANF
Natriuretic peptides A

1

0

High-throughput

0.279

Low

469205

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.279

Low

518912

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

630040

BTF3
Transcription factor BTF3

1

0

High-throughput

0.279

Low

706317

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

709013

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.279

Low

883694

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.279

Low

913167

STAT2
Signal transducer and activator of transcription 2

1

0

High-throughput

0.279

Low

1101423

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1122896

TFDP2
Transcription factor Dp-2

1

0

High-throughput

0.279

Low

1180964

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.279

Low

1209009

PPR29
Protein phosphatase 1 regulatory subunit 29

1

0

High-throughput

0.279

Low

1215565

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.279

Low

1248882

ENPP7
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

1

0

High-throughput

0.279

Low

1294975

LRC33
Transforming growth factor beta activator LRRC33

1

0

High-throughput

0.279

Low

1315329

ZDH23
Palmitoyltransferase ZDHHC23

1

0

High-throughput

0.279

Low

1359323

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.279

Low

1389506

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

1413147

SPXN
Spexin

1

0

High-throughput

0.279

Low

1418675

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.279

Low

1437047

ARP5
Actin-related protein 5

1

0

High-throughput

0.279

Low

1438286

MMP26
Matrix metalloproteinase-26

1

0

High-throughput

0.279

Low

1438288

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.279

Low

1438293

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

1438294

TACC3
Transforming acidic coiled-coil-containing protein 3

1

0

High-throughput

0.279

Low

1274112

PRS48
Serine protease 48

1

0

High-throughput

0.269

Low

218799

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

294351

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

647407

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.249

Low

831458

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

988725

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.249

Low

1137163

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.249

Low

1250923

ZPBP2
Zona pellucida-binding protein 2

1

0

High-throughput

0.249

Low

1412672

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low

1438291

MYO5B
Unconventional myosin-Vb

1

0

High-throughput

0.249

Low

1359248

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025