Protein: SOCS1
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)

Gene: SOCS1
Organism: Mus musculus
Interactions: 25
UniProt ID: O35716

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0005159 - insulin-like growth factor receptor binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

205427

ELOC
Elongin-C

3

10

Small-scale

0.866

High

205417

KIT
Mast/stem cell growth factor receptor Kit

3

20

Small-scale

0.814

High

205433

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.786

High

205430

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

7

Small-scale

0.713

High

73017

B1ASP2
Tyrosine-protein kinase

1

20

Small-scale

0.647

High

205438

CUL5
Cullin-5

1

20

Small-scale

0.647

High

205426

ELOB
Elongin-B

2

10

Small-scale

0.634

High

205418

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

20

Small-scale

0.621

High

205416

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.618

High

205419

INSR
Insulin receptor

1

20

Small-scale

0.618

High

205428

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.618

High

205439

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.555

High

205437

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

Small-scale

0.552

High

205420

INGR1
Interferon gamma receptor 1

2

6

Small-scale

0.549

High

205432

PIM2
Serine/threonine-protein kinase pim-2

1

15

Small-scale

0.512

High

205422

IRF8
Interferon regulatory factor 8

1

7

High-throughput

0.479

High

205425

PCNT
Pericentrin

1

6

Small-scale

0.479

High

205429

TF65
Transcription factor p65

1

10

Small-scale

0.479

High

205434

TIF1B
Transcription intermediary factor 1-beta

1

17

Small-scale

0.479

High

205435

BCLF1
Bcl-2-associated transcription factor 1

1

6

Small-scale

0.479

High

205431

5NTC
Cytosolic purine 5'-nucleotidase

1

0

Small-scale

0.458

High

205421

IRF1
Interferon regulatory factor 1

1

7

Small-scale

0.437

High

205424

INAR1
Interferon alpha/beta receptor 1

1

19

Small-scale

0.437

High

205436

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

3

Small-scale

0.437

High

205423

PCSK4
Proprotein convertase subtilisin/kexin type 4

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025