HitPredict

Interactor 1: SOCS1 (O35716)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)
Gene: SOCS1

Interactor 2: INAR1 (P33896)
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Type I interferon receptor 1)
Gene: Ifnar1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21757742
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 212 Mm			1 590
+	Hs
		193203 SOCS1_HUMAN (1-212): 6.61e-47: 155: 94.81		INAR1_HUMAN (1-540): 8.63e-108: 336: 49.27
+	Hs
		602865 P85A_HUMAN (76-181): 3.54e-17: 81.3: 23.59		INAR1_HUMAN (1-540): 8.63e-108: 336: 49.27
+	Hs
		440313 FYN_HUMAN (69-195): 3.07e-37: 137: 18.98		PTPRF_HUMAN (1-517): 1.2e-56: 208: 12.46
+	Hs
		193197 SOCS1_HUMAN (1-212): 6.61e-47: 155: 94.81		INGR1_HUMAN (2-224): 4.05e-46: 171: 16.25
+	Mm
		205420 SOCS1_MOUSE (1-212): 2.82e-52: 169: 100.00		INGR1_MOUSE (26-347): 5.61e-39: 151: 15.00
+	Hs
		1364891 P55G_HUMAN (38-175): 1.66e-23: 99: 15.22		I20RA_HUMAN (20-293): 3.97e-63: 219: 22.34
+	Hs
		699884 P85A_HUMAN (76-181): 3.54e-17: 81.3: 23.59		I20RA_HUMAN (20-293): 3.97e-63: 219: 22.34
+	Dm
		55056 ABL_DROME (8-193): 1.97e-37: 139: 15.15		A1Z921_DROME (28-450): 6.59e-24: 109: 14.48
+	Hs
		319121 NCK1_HUMAN (4-175): 3.06e-40: 142: 18.39		NFASC_HUMAN (2-557): 2.77e-22: 103: 10.61
+	Mm
		59107 FYN_MOUSE (69-195): 3.07e-37: 137: 18.98		PTPRF_MOUSE (99-526): 1.54e-23: 108: 9.03
+	Hs
		319119 FYN_HUMAN (69-195): 3.07e-37: 137: 18.98		NFASC_HUMAN (2-557): 2.77e-22: 103: 10.61
+	Hs
		440539 FYN_HUMAN (69-195): 3.07e-37: 137: 18.98		PTPRS_HUMAN (144-587): 7.12e-22: 102: 9.42
+	Hs
		440371 FYN_HUMAN (69-195): 3.07e-37: 137: 18.98		PTPRD_HUMAN (197-587): 1.69e-20: 98.5: 9.55
+	Hs
		155917 SOCS3_HUMAN (40-208): 3.44e-42: 143: 27.27		IL6RB_HUMAN (228-432): 2.55e-17: 88.1: 16.97
+	Hs
		249091 NCK1_HUMAN (4-175): 3.06e-40: 142: 18.39		DSCAM_HUMAN (305-554): 3.76e-15: 81.6: 9.13
+	Hs
		473376 HCK_HUMAN (13-196): 5.88e-36: 133: 13.68		IL6RB_HUMAN (228-432): 2.55e-17: 88.1: 16.97
+	Hs
		593937 NCK1_HUMAN (4-175): 3.06e-40: 142: 18.39		DCC_HUMAN (28-415): 1.58e-13: 76.1: 14.39
+	Mm
		205465 SOCS3_MOUSE (38-208): 1.26e-42: 144: 27.35		IL6RB_MOUSE (4-214): 2.5e-09: 62.2: 12.33
+	Hs
		699622 P85A_HUMAN (76-181): 3.54e-17: 81.3: 23.59		IL6RB_HUMAN (228-432): 2.55e-17: 88.1: 16.97