Protein: TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein)

Gene: TIRAP
Organism: Mus musculus
Interactions: 10
UniProt ID: Q99JY1

Gene Ontology (top 5):
GO:0005080 - protein kinase C binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

648076

MYD88
Myeloid differentiation primary response protein MyD88

2

6

Small-scale

0.754

High

1188873

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.586

High

1408753

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

1

Small-scale

0.515

High

1341612

IRAK4
Interleukin-1 receptor-associated kinase 4

1

2

Small-scale

0.481

High

1408754

TLR4
Toll-like receptor 4

1

3

Small-scale

0.481

High

686985

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.479

High

834705

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

1

Small-scale

0.479

High

1223816

RAGE
Advanced glycosylation end product-specific receptor

1

1

Small-scale

0.445

High

205436

SOCS1
Suppressor of cytokine signaling 1

1

3

Small-scale

0.437

High

205665

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

0

Small-scale

0.426

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025