Protein: RPA43
DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein)

Gene: RPA43, POLR1F
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q3B726

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
GO:0006352 - DNA-templated transcription initiation
GO:0006362 - transcription elongation by RNA polymerase I
GO:1990830 - cellular response to leukemia inhibitory factor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339987

RPA1
DNA-directed RNA polymerase I subunit RPA1

4

1

High-throughput

0.903

High

1185170

RPA2
DNA-directed RNA polymerase I subunit RPA2

4

1

High-throughput

0.903

High

1185171

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

3

1

High-throughput

0.861

High

958957

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.691

High

180300

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

3

1

High-throughput

0.675

High

1185167

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.628

High

190932

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.585

High

396233

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

372180

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

621888

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

923498

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

983662

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.536

High

1185172

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.536

High

732611

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

854091

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1134457

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.513

High

1185162

INT8
Integrator complex subunit 8

1

0

High-throughput

0.513

High

1185168

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.513

High

220087

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

1

High-throughput

0.489

High

642559

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.489

High

879155

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

1185177

FBW1A
F-box/WD repeat-containing protein 1A

1

1

High-throughput

0.479

High

1185178

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

1

High-throughput

0.479

High

247943

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

260039

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

325866

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

342899

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

711643

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

1185163

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1185169

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1185173

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1185179

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

516844

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.445

High

1185159

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1185174

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.437

High

1185175

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

516797

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

563847

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

600229

ZNF23
Zinc finger protein 23

1

0

High-throughput

0.279

Low

1097250

S13A2
Solute carrier family 13 member 2

1

0

High-throughput

0.279

Low

1185166

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.279

Low

786638

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.265

Low

1185164

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

0

High-throughput

0.251

Low

241851

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

345897

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

1049347

1433F
14-3-3 protein eta

1

0

High-throughput

0.249

Low

1185160

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1185161

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1185165

FIG4
Polyphosphoinositide phosphatase

1

0

High-throughput

0.249

Low

1185176

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025