Protein: SUMO3
Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A)

Gene: SUMO3
Organism: Homo sapiens
Interactions: 116
UniProt ID: P55854

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016605 - PML body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

879101

UBC9
SUMO-conjugating enzyme UBC9

7

18

Small-scale

0.965

High

879156

SENP2
Sentrin-specific protease 2

5

20

Small-scale

0.938

High

879158

SENP1
Sentrin-specific protease 1

3

20

Small-scale

0.868

High

278250

PIAS2
E3 SUMO-protein ligase PIAS2

3

20

Small-scale

0.841

High

278009

PIAS1
E3 SUMO-protein ligase PIAS1

2

20

Small-scale

0.800

High

316316

TYDP2
Tyrosyl-DNA phosphodiesterase 2

2

2

Small-scale

0.800

High

879159

SAE1
SUMO-activating enzyme subunit 1

2

10

High-throughput

0.776

High

879097

SUMO2
Small ubiquitin-related modifier 2

1

11

High-throughput

0.691

High

879111

TDG
G/T mismatch-specific thymine DNA glycosylase

1

2

Small-scale

0.680

High

879124

ZCH12
Zinc finger CCHC domain-containing protein 12

3

2

High-throughput

0.667

High

879147

SENP5
Sentrin-specific protease 5

1

20

Small-scale

0.647

High

879167

PIAS3
E3 SUMO-protein ligase PIAS3

1

20

Small-scale

0.647

High

668550

PML
Protein PML

3

10

Small-scale

0.633

High

879122

USPL1
SUMO-specific isopeptidase USPL1

3

2

Small-scale

0.629

High

879163

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

2

8

Small-scale

0.619

High

879096

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.618

High

879108

EP300
Histone acetyltransferase p300

1

11

Small-scale

0.618

High

879160

SAE2
SUMO-activating enzyme subunit 2

1

9

Small-scale

0.618

High

617270

SP100
Nuclear autoantigen Sp-100

2

12

Small-scale

0.611

High

166068

ZBT39
Zinc finger and BTB domain-containing protein 39

2

2

High-throughput

0.606

High

879129

KAISO
Transcriptional regulator Kaiso

2

3

High-throughput

0.606

High

879148

ZN496
Zinc finger protein 496

2

2

High-throughput

0.606

High

879136

PIAS4
E3 SUMO-protein ligase PIAS4

1

20

High-throughput

0.590

High

879149

ATX2
Ataxin-2

2

4

Small-scale

0.588

High

879103

RNF4
E3 ubiquitin-protein ligase RNF4

2

10

Small-scale

0.584

High

282587

RNF8
E3 ubiquitin-protein ligase RNF8

1

12

Small-scale

0.561

High

879134

SLX4
Structure-specific endonuclease subunit SLX4

1

8

Small-scale

0.561

High

441977

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.541

High

443429

VIME
Vimentin

1

6

High-throughput

0.541

High

641356

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.541

High

718383

PCGF2
Polycomb group RING finger protein 2

1

4

High-throughput

0.541

High

879112

MORC3
MORC family CW-type zinc finger protein 3

1

1

High-throughput

0.541

High

879131

HIPK1
Homeodomain-interacting protein kinase 1

1

10

High-throughput

0.541

High

879144

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

879161

ZMYM2
Zinc finger MYM-type protein 2

1

7

High-throughput

0.541

High

879164

ARIP4
Helicase ARIP4

1

20

High-throughput

0.541

High

879165

ZN451
E3 SUMO-protein ligase ZNF451

1

2

High-throughput

0.541

High

879130

CARM1
Histone-arginine methyltransferase CARM1

1

4

High-throughput

0.536

High

879109

CAF1A
Chromatin assembly factor 1 subunit A

1

5

Small-scale

0.527

High

879106

CAV1
Caveolin-1

2

1

High-throughput

0.521

High

879121

SYDE2
Rho GTPase-activating protein SYDE2

2

2

High-throughput

0.521

High

791424

HD
Huntingtin

1

2

High-throughput

0.515

High

868394

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

176417

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

378661

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

589171

ANXA7
Annexin A7

1

5

High-throughput

0.508

High

879107

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.508

High

879115

MAPK3
MAP kinase-activated protein kinase 3

1

4

High-throughput

0.508

High

808435

YAP1
Transcriptional coactivator YAP1

1

3

Small-scale

0.501

High

879125

RN111
E3 ubiquitin-protein ligase Arkadia

1

5

Small-scale

0.501

High

879150

WWTR1
WW domain-containing transcription regulator protein 1

1

3

Small-scale

0.501

High

879151

HIPK2
Homeodomain-interacting protein kinase 2

1

8

Small-scale

0.501

High

879154

EGLN3
Prolyl hydroxylase EGLN3

1

3

Small-scale

0.501

High

879162

DAXX
Death domain-associated protein 6

1

5

Small-scale

0.501

High

199693

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

4

Small-scale

0.500

High

725636

ACTN2
Alpha-actinin-2

1

7

High-throughput

0.489

High

245953

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.486

High

758167

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

879114

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

879133

HOMEZ
Homeobox and leucine zipper protein Homez

1

8

High-throughput

0.481

High

123211

CBX4
E3 SUMO-protein ligase CBX4

1

4

Small-scale

0.479

High

162553

XPO1
Exportin-1

1

6

High-throughput

0.479

High

244184

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

386398

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

418080

NPM
Nucleophosmin

1

2

Small-scale

0.479

High

475534

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

Small-scale

0.479

High

510011

ERR1
Steroid hormone receptor ERR1

1

10

Small-scale

0.479

High

796715

RANG
Ran-specific GTPase-activating protein

1

7

High-throughput

0.479

High

823764

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

874372

NR1H2
Oxysterols receptor LXR-beta

1

9

Small-scale

0.479

High

879095

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

879098

ERR3
Estrogen-related receptor gamma

1

10

Small-scale

0.479

High

879099

H4
Histone H4

1

3

High-throughput

0.479

High

879100

RAN
GTP-binding nuclear protein Ran

1

4

High-throughput

0.479

High

879102

H31
Histone H3.1

1

5

High-throughput

0.479

High

879104

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

879116

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.479

High

879123

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

879127

ARC
Activity-regulated cytoskeleton-associated protein

1

3

Small-scale

0.479

High

879135

RN168
E3 ubiquitin-protein ligase RNF168

1

4

Small-scale

0.479

High

879143

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

879153

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

363579

TTHY
Transthyretin

1

2

High-throughput

0.464

High

879155

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.460

High

373950

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

879119

MIDN
Midnolin

1

0

High-throughput

0.458

High

789138

HELZ
Probable helicase with zinc finger domain

1

3

Small-scale

0.445

High

801659

RAGP1
Ran GTPase-activating protein 1

1

5

Small-scale

0.445

High

834008

CLK3
Dual specificity protein kinase CLK3

1

3

Small-scale

0.445

High

879105

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

1

Small-scale

0.445

High

879110

RLF
Zinc finger protein Rlf

1

1

Small-scale

0.445

High

879113

NEDD8
NEDD8

1

4

Small-scale

0.445

High

879117

H2B2E
Histone H2B type 2-E

1

3

Small-scale

0.445

High

879118

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

1

Small-scale

0.445

High

879120

BEND3
BEN domain-containing protein 3

1

1

Small-scale

0.445

High

879126

DHX30
ATP-dependent RNA helicase DHX30

1

4

Small-scale

0.445

High

879137

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

7

Small-scale

0.445

High

879139

ARI1B
AT-rich interactive domain-containing protein 1B

1

4

Small-scale

0.445

High

879142

DDB2
DNA damage-binding protein 2

1

1

Small-scale

0.445

High

879146

RBM33
RNA-binding protein 33

1

5

Small-scale

0.445

High

879157

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

11

Small-scale

0.445

High

879166

NCOR2
Nuclear receptor corepressor 2

1

8

Small-scale

0.445

High

608263

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

5

Small-scale

0.437

High

129971

MEIS1
Homeobox protein Meis1

1

0

Small-scale

0.426

High

879128

NUFP2
FMR1-interacting protein NUFIP2

1

0

Small-scale

0.426

High

879138

FA98A
Protein FAM98A

1

0

Small-scale

0.426

High

879145

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

Small-scale

0.426

High

398508

PPB1
Alkaline phosphatase, placental type

1

1

Small-scale

0.407

High

646154

STOM
Stomatin

1

2

Small-scale

0.407

High

879132

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

1

1

Small-scale

0.407

High

879141

ATX2L
Ataxin-2-like protein

1

3

Small-scale

0.407

High

879152

ZN106
Zinc finger protein 106

1

3

Small-scale

0.407

High

59509

F221A
Protein FAM221A

2

0

High-throughput

0.316

High

866913

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.249

Low

879140

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

674642

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024