Protein: HDDC2
5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) (Hepatitis C virus NS5A-transactivated protein 2) (HCV NS5A-transactivated protein 2)

Gene: HDDC2
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q7Z4H3

Gene Ontology (top 5):
GO:0002953 - 5'-deoxynucleotidase activity
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

242129

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.437

High

703954

DUS1
Dual specificity protein phosphatase 1

1

2

High-throughput

0.437

High

1163845

DUS6
Dual specificity protein phosphatase 6

1

2

High-throughput

0.437

High

1278390

DUS19
Dual specificity protein phosphatase 19

1

3

High-throughput

0.437

High

1278393

DUS23
Dual specificity protein phosphatase 23

1

4

High-throughput

0.437

High

1278396

DUS12
Dual specificity protein phosphatase 12

1

3

High-throughput

0.437

High

377062

COLI
Pro-opiomelanocortin

2

0

High-throughput

0.316

High

1009672

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.316

High

1278397

NEMO
NF-kappa-B essential modulator

2

0

High-throughput

0.316

High

1205848

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

106182

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

830984

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

970709

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1278391

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

0

High-throughput

0.249

Low

1278392

FMNL2
Formin-like protein 2

1

0

High-throughput

0.249

Low

1278394

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1278395

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

404827

PRIO
Major prion protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025