Protein: TFE3
Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33)

Gene: TFE3
Organism: Homo sapiens
Interactions: 74
UniProt ID: P19532

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585106

TFEB
Transcription factor EB

4

13

Small-scale

0.903

High

252903

MITF
Microphthalmia-associated transcription factor

4

13

Small-scale

0.895

High

159435

TFEC
Transcription factor EC

1

13

Small-scale

0.647

High

585624

TFE3
Transcription factor E3

1

12

Small-scale

0.647

High

585676

LTOR3
Ragulator complex protein LAMTOR3

2

1

High-throughput

0.606

High

585649

SMAD3
Mothers against decapentaplegic homolog 3

2

4

Small-scale

0.602

High

585658

SMAD4
Mothers against decapentaplegic homolog 4

2

4

Small-scale

0.602

High

585630

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

585644

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

585656

TIF1B
Transcription intermediary factor 1-beta

2

5

Small-scale

0.601

High

135208

E2F3
Transcription factor E2F3

1

3

Small-scale

0.573

High

585677

FBW1B
F-box/WD repeat-containing protein 11

1

12

Small-scale

0.561

High

585679

FBW1A
F-box/WD repeat-containing protein 1A

1

11

Small-scale

0.527

High

544725

ALDR
Aldo-keto reductase family 1 member B1

1

1

High-throughput

0.515

High

585629

SYVC
Valine--tRNA ligase

1

1

High-throughput

0.515

High

585633

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.515

High

585638

ACLY
ATP-citrate synthase

1

2

High-throughput

0.515

High

585650

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.515

High

585671

PHB2
Prohibitin-2

1

1

High-throughput

0.515

High

157005

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.513

High

585668

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

2

Small-scale

0.501

High

166404

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.493

High

430863

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.493

High

585648

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.493

High

585659

CUL2
Cullin-2

1

0

High-throughput

0.493

High

585662

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.493

High

585664

NEDD8
NEDD8

1

0

High-throughput

0.493

High

162397

XPO1
Exportin-1

1

7

High-throughput

0.479

High

178106

IPO8
Importin-8

1

1

Small-scale

0.479

High

183062

KDM6A
Lysine-specific demethylase 6A

1

2

Small-scale

0.479

High

211794

TLX3
T-cell leukemia homeobox protein 3

1

6

High-throughput

0.479

High

316787

KLF8
Krueppel-like factor 8

1

13

High-throughput

0.479

High

377079

GCR
Glucocorticoid receptor

1

10

High-throughput

0.479

High

585626

GSTM3
Glutathione S-transferase Mu 3

1

1

High-throughput

0.479

High

585627

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

585628

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.479

High

585635

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

585636

NASP
Nuclear autoantigenic sperm protein

1

1

High-throughput

0.479

High

585639

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

585640

NP1L1
Nucleosome assembly protein 1-like 1

1

3

High-throughput

0.479

High

585641

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

585642

KLF3
Krueppel-like factor 3

1

13

High-throughput

0.479

High

585643

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.479

High

585645

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

7

High-throughput

0.479

High

585646

H4
Histone H4

1

11

High-throughput

0.479

High

585647

SUMO1
Small ubiquitin-related modifier 1

1

4

Small-scale

0.479

High

585651

SET
Protein SET

1

3

High-throughput

0.479

High

585652

EWS
RNA-binding protein EWS

1

7

High-throughput

0.479

High

585653

IRF8
Interferon regulatory factor 8

1

1

High-throughput

0.479

High

585654

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.479

High

585655

TADBP
TAR DNA-binding protein 43

1

3

Small-scale

0.479

High

585657

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

7

High-throughput

0.479

High

585661

KLF5
Krueppel-like factor 5

1

12

High-throughput

0.479

High

585666

RRAGA
Ras-related GTP-binding protein A

1

9

Small-scale

0.479

High

585667

PDC6I
Programmed cell death 6-interacting protein

1

10

High-throughput

0.479

High

585672

KLF16
Krueppel-like factor 16

1

12

High-throughput

0.479

High

585674

RRAGC
Ras-related GTP-binding protein C

1

9

Small-scale

0.479

High

585675

VSX1
Visual system homeobox 1

1

3

High-throughput

0.479

High

585678

HDAC5
Histone deacetylase 5

1

10

Small-scale

0.479

High

585680

KLF12
Krueppel-like factor 12

1

12

High-throughput

0.479

High

273686

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

311475

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.458

High

585625

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

585634

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

585637

SPSY
Spermine synthase

1

0

High-throughput

0.458

High

585665

FSCN1
Fascin

1

0

High-throughput

0.458

High

585670

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

585673

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

585632

BMI1
Polycomb complex protein BMI-1

1

6

High-throughput

0.445

High

585660

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.445

High

585669

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

1

High-throughput

0.437

High

585631

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

585663

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024