Protein: SIM12
Small integral membrane protein 12

Gene: SIM12, SMIM12
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q96EX1

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1196943

MIX23
Protein MIX23

4

0

High-throughput

0.648

High

348654

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

0

High-throughput

0.559

High

560046

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

951343

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1389842

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

280771

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

562306

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

1389849

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

1389838

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

174041

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

292196

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

296281

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

418347

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

820713

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

847642

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

904062

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1058583

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1312216

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.458

High

1366513

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1389829

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1389830

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

1389831

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1389832

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

1389835

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.458

High

1389836

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1389837

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1389840

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1389841

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1389843

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1389844

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1389845

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1389846

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.458

High

1389847

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1389834

USB1
U6 snRNA phosphodiesterase 1

1

1

High-throughput

0.437

High

329328

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.426

High

116356

H3BTS1
U6 snRNA biogenesis phosphodiesterase 1

1

1

High-throughput

0.407

High

1389833

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.279

Low

1389848

IL36A
Interleukin-36 alpha

1

0

High-throughput

0.279

Low

900984

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.249

Low

1333945

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1389839

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025