Protein: FBH1
F-box DNA helicase 1 (hFBH1) (EC 5.6.2.4) (DNA 3'-5' helicase 1) (F-box only protein 18)

Gene: FBH1
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q8NFZ0

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000785 - chromatin
GO:0001934 - positive regulation of protein phosphorylation
GO:0003678 - DNA helicase activity
GO:0003690 - double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992264

SKP1
S-phase kinase-associated protein 1

9

1

Small-scale

0.973

High

1112607

CUL1
Cullin-1

8

0

Small-scale

0.916

High

983893

RBX1
E3 ubiquitin-protein ligase RBX1

4

0

Small-scale

0.660

High

1055945

RAD51
DNA repair protein RAD51 homolog 1

3

0

Small-scale

0.623

High

242340

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.618

High

508300

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.614

High

1307578

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.584

High

551166

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.577

High

589205

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.559

High

695988

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.559

High

768688

RFA3
Replication protein A 14 kDa subunit

2

0

Small-scale

0.559

High

372626

MYC
Myc proto-oncogene protein

1

0

Small-scale

0.537

High

1217889

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

0

Small-scale

0.537

High

250719

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

1144085

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

127142

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.493

High

843786

HD
Huntingtin

1

0

High-throughput

0.493

High

1328100

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.489

High

396555

ESR1
Estrogen receptor

1

0

Small-scale

0.480

High

461726

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

468613

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.479

High

1339599

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

557394

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

Small-scale

0.458

High

718898

CCND3
G1/S-specific cyclin-D3

1

0

Small-scale

0.458

High

1339596

DTL
Denticleless protein homolog

1

0

Small-scale

0.458

High

1339598

XPO7
Exportin-7

1

0

High-throughput

0.458

High

824244

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.438

High

1339597

PIM2
Serine/threonine-protein kinase pim-2

1

0

High-throughput

0.438

High

539828

RALA
Ras-related protein Ral-A

1

0

High-throughput

0.279

Low

1009258

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1339593

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.279

Low

1339594

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

0

High-throughput

0.279

Low

301579

WFS1
Wolframin

1

0

High-throughput

0.268

Low

705475

GRN
Progranulin

1

0

High-throughput

0.268

Low

947023

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

1339595

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025