Protein: ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16)

Gene: ILKAP
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9H0C8

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

187179

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.691

High

163162

CHK1
Serine/threonine-protein kinase Chk1

1

20

Small-scale

0.647

High

908171

KS6A3
Ribosomal protein S6 kinase alpha-3

1

5

Small-scale

0.647

High

1158179

MK14
Mitogen-activated protein kinase 14

1

14

Small-scale

0.647

High

1104480

ILK
Scaffold protein ILK

1

5

Small-scale

0.573

High

179635

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.541

High

363834

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.541

High

411043

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.541

High

465640

IGF1R
Insulin-like growth factor 1 receptor

1

18

High-throughput

0.541

High

532101

KIT
Mast/stem cell growth factor receptor Kit

1

12

High-throughput

0.541

High

641671

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.541

High

1034190

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.541

High

1034337

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.541

High

1038475

TIE2
Angiopoietin-1 receptor

1

7

High-throughput

0.541

High

1101774

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.541

High

1145776

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

123824

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.536

High

227964

MYO1B
Unconventional myosin-Ib

1

1

High-throughput

0.536

High

1106696

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.536

High

1349976

CERK1
Ceramide kinase

1

2

High-throughput

0.536

High

562644

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.513

High

838389

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.513

High

973579

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

1160754

DREB
Drebrin

1

0

High-throughput

0.513

High

1367920

TAF4B
Transcription initiation factor TFIID subunit 4B

1

0

High-throughput

0.513

High

186010

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

710475

EPHA2
Ephrin type-A receptor 2

1

8

High-throughput

0.494

High

710658

EPHA3
Ephrin type-A receptor 3

1

8

High-throughput

0.494

High

778100

VGFR2
Vascular endothelial growth factor receptor 2

1

12

High-throughput

0.494

High

1251955

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

1310874

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

317923

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.489

High

814860

CUX1
Homeobox protein cut-like 1

1

2

High-throughput

0.489

High

1142661

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.489

High

169742

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.480

High

1429776

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

242867

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

320045

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

658980

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

2

High-throughput

0.479

High

714412

PML
Protein PML

1

2

High-throughput

0.479

High

1255465

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1393678

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1429774

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1279738

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

607092

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

785436

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

986706

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1313418

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1395574

MAEL
Protein maelstrom homolog

1

0

Small-scale

0.458

High

1380310

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

2

Small-scale

0.457

High

1429773

PTPRH
Receptor-type tyrosine-protein phosphatase H

1

2

High-throughput

0.445

High

209333

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.437

High

260432

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.437

High

386212

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.437

High

487737

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.437

High

558394

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.437

High

589641

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

696456

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769130

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

971057

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1008338

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.437

High

1017195

H33
Histone H3.3

1

2

High-throughput

0.437

High

1096810

RFA4
Replication protein A 30 kDa subunit

1

3

High-throughput

0.437

High

1100361

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

1429775

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

2

High-throughput

0.437

High

1429777

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

430345

JUN
Transcription factor Jun

1

1

High-throughput

0.407

High

658834

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

2

High-throughput

0.407

High

278742

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.328

High

1358197

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.328

High

1391039

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.298

High

726619

CASQ1
Calsequestrin-1

1

0

High-throughput

0.279

Low

908619

LUM
Lumican

1

0

High-throughput

0.279

Low

943861

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.279

Low

995475

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.279

Low

1273209

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.279

Low

1339594

FBH1
F-box DNA helicase 1

1

0

High-throughput

0.279

Low

846469

MATR3
Matrin-3

1

0

High-throughput

0.269

Low

215184

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.249

Low

663447

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.249

Low

915487

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.249

Low

981080

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.249

Low

1097549

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.249

Low

1276765

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1289614

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1314410

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

1397105

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

1429772

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025