Protein: RN121
E3 ubiquitin ligase RNF121 (EC 2.3.2.27) (RING finger protein 121)

Gene: RN121, RNF121
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q9H920

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0036503 - ERAD pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396970

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

1391512

BSCL2
Seipin

1

0

High-throughput

0.513

High

1436749

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

133800

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

1365508

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.458

High

1433181

PIGU
GPI-anchor transamidase component PIGU

1

0

Small-scale

0.458

High

869674

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

2

High-throughput

0.407

High

870314

S6A12
Sodium- and chloride-dependent betaine transporter

1

2

High-throughput

0.407

High

1436748

S6A13
Sodium- and chloride-dependent GABA transporter 2

1

2

High-throughput

0.407

High

1366243

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.279

Low

1417371

CCG6
Voltage-dependent calcium channel gamma-6 subunit

1

0

High-throughput

0.279

Low

683517

IKBA
NF-kappa-B inhibitor alpha

1

0

Small-scale

0.249

Low

901579

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

1331254

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.249

Low

1236324

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025