Protein: PRUN1
Exopolyphosphatase PRUNE1 (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37) (Protein prune homolog 1) (hPrune)

Gene: PRUN1, PRUNE1
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q86TP1

Gene Ontology (top 5):
GO:0004309 - exopolyphosphatase activity
GO:0004427 - inorganic diphosphate phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

891652

GSK3B
Glycogen synthase kinase-3 beta

6

1

High-throughput

0.735

High

891225

GSK3A
Glycogen synthase kinase-3 alpha

3

1

High-throughput

0.671

High

1287505

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

3

0

High-throughput

0.638

High

1287501

NPAS1
Neuronal PAS domain-containing protein 1

2

0

High-throughput

0.602

High

584773

NDKA
Nucleoside diphosphate kinase A

1

0

Small-scale

0.549

High

1270810

RUFY3
Protein RUFY3

1

0

High-throughput

0.493

High

777715

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.479

High

293943

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

791499

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

970717

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1254447

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1287495

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1287498

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1287502

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1287506

DUS10
Dual specificity protein phosphatase 10

1

0

High-throughput

0.458

High

412182

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

648571

FGFR4
Fibroblast growth factor receptor 4

1

2

High-throughput

0.437

High

142221

CCL22
C-C motif chemokine 22

2

0

High-throughput

0.328

High

239273

GMFG
Glia maturation factor gamma

2

0

High-throughput

0.328

High

1251064

SG1D4
Secretoglobin family 1D member 4

2

0

High-throughput

0.328

High

1254117

INSY2
Inhibitory synaptic factor 2A

2

0

High-throughput

0.328

High

1287496

PIANP
PILR alpha-associated neural protein

2

0

High-throughput

0.328

High

1206194

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

1208207

SPXN5
Sperm protein associated with the nucleus on the X chromosome N5

1

0

High-throughput

0.279

Low

1287499

RAB2B
Ras-related protein Rab-2B

1

0

High-throughput

0.279

Low

1287500

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

1287503

GTSFL
Gametocyte-specific factor 1-like

1

0

High-throughput

0.279

Low

642953

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

673778

LAMA1
Laminin subunit alpha-1

1

0

High-throughput

0.249

Low

1287497

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1287504

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025